Progression of dilated cardiomyopathy: comparison of left ventricular ejection fractions at study entry and follow up for patients with a follow up LVEF
| I: index patients, familial | II: index patients, non-familial | I v II, p value | Affected relatives | |
|---|---|---|---|---|
| LVEF, left ventricular ejection fraction. | ||||
| Number of patients | 20 | 44 | 20 | |
| Age at study entry (years) (mean (SD)) | 51.3 (14.4) | 48.3 (16.1) | 0.471 | 44.6 (14.8) |
| Range | (18.4 to 72.5) | (6.5 to 72.7) | (14.1 to 64.2) | |
| Time to follow up LVEF (years) (mean (SD)) | 5.9 (4.2) | 6.3 (4.0) | 0.746 | 8.3 (3.4) |
| Range | (0.6 to 12.4) | (0.2 to 12.4) | (1.0 to 12.3) | |
| LVEF at study entry (%) (mean (SD)) | 28.9 (14.1) | 25.8 (9.9) | 0.392 | 40.8 (17.1) |
| Range | (13 to 62) | (12 to 50) | (14 to 65) | |
| LVEF at follow up (%) (mean (SD)) | 30.3 (16.2) | 29.0 (16.0) | 0.76 | 43.4 (17.1) |
| Range | (10 to 62) | (8 to 63) | (14 to 65) | |
| Difference in LVEF between entry and follow up (%) (mean (SD)) | 1.5 (15.9) | 3.1 (14.0) | 0.686 | 2.6 (8.6) |
| Range | (−33 to 34) | (−23 to 42) | (−13 to 16) | |
| Number with increased LVEF | 10 | 19 | 7 | |
| Increase in LVEF (%) (mean (SD)) | 13.0 (12.0) | 15.1 (12.9) | 0.666 | 8.6 (4.5) |
| Range | (1 to 34) | (1 to 42) | (3 to 16) | |
| Number with decreased LVEF | 9 | 22 | 4 | |
| Decrease in LVEF (%) (mean (SD)) | −11.2 (9.6) | −6.8 (5.1) | 0.22 | −7.3 (4.2) |
| Range | (−33 to −2) | (−23 to −1) | (−13 to −3) | |
| Number with no change in LVEF | 1 | 3 | 1 | |