Comparison of the left ventricular ejection fraction in patients with serum ferritin concentration < 1000 ng/ml (group 1), 1000–2500 ng/ml (group 2), and > 2500 ng/ml (group 3)
| Variable | Group 1 (n=124) | Group 2 (n=49) | Group 3 (n=24) | Gp 1 v gp 2 | Gp 1 v gp 3 | Gp 2 v gp 3 |
|---|---|---|---|---|---|---|
| Values are mean (SD). | ||||||
| *Mean value of previous year. | ||||||
| EF, ejection fraction; Hb, haemoglobin. | ||||||
| Age (years) | 26.8 (5.8) | 23.5 (6.0) | 24.6 (4.5) | <0.01 | NS | NS |
| Age at diagnosis (years) | 1.45 (2.77) | 1.32 (1.55) | 1.03 (0.90) | NS | NS | NS |
| Follow up (years) | 25.4 (6.1) | 22.1 (6.3) | 23.5 (4.5) | <0.01 | NS | NS |
| Hb (g/dl)* | 8.9 (0.5) | 9.3 (0.7) | 9.0 (0.6) | <0.001 | NS | NS |
| Serum ferritin (ng/ml)* | 593 (195) | 1670 (427) | 3975 (1624) | <0.0001 | <0.0001 | <0.001 |
| Transfusion therapy (years) | 25.1 (6.0) | 22.9 (6.3) | 23.5 (4.5) | <0.01 | NS | NS |
| Chelation therapy (years) | 20.1 (2.9) | 18.5 (4.2) | 19.2 (2.3) | <0.01 | NS | NS |
| EF (%) | 57.0 (6.1) | 55.8 (7.7) | 52.1 (8.4) | NS | <0.001 | NS |