Traditional cardiovascular risk factors in patients with severe aortic stenosis and in controls with normal aortic valves (not matched)
| Severe aortic stenosis | Normal aortic valve | p Value | Odds ratio (95% CI) | |
|---|---|---|---|---|
| Values are n (%) unless stated. | ||||
| CI, confidence interval; FH, family history. | ||||
| n | 523 | 3925 | ||
| Age (years) (mean (SD)) | 70 (8) | 61 (11) | <0.001 | |
| Clear coronaries or coronary sclerosis | 246 (47%) | 1426 (36%) | ||
| Stenosis of >50% in at least one coronary vessel | 277 (53%) | 2499 (64%) | ||
| Cardiovascular risk factors | ||||
| Male sex | 287 (55%) | 2642 (67%) | 0.001 | 0.59 (0.49 to 0.71) |
| Hypertension | 308 (59%) | 2282 (58%) | 0.777 | 1.03 (0.86 to 1.24) |
| Hypercholesterolaemia | 258 (49%) | 2623 (67%) | 0.001 | 0.49 (0.40 to 0.58) |
| Smoking | 213 (41%) | 1807 (46%) | 0.022 | 0.81 (0.67 to 0.97) |
| FH of coronary artery disease | 144 (28%) | 1289 (33%) | 0.015 | 0.78 (0.63 to 0.95) |
| Diabetes mellitus | 106 (20%) | 699 (18%) | 0.183 | 1.17 (0.93 to 1.47) |