Demographic data
| Placebo | 10 mg lexipafant | 100 mg lexipafant | Total | |
|---|---|---|---|---|
| Continuous variables are mean (SD). CPB, cardiopulmonary bypass. | ||||
| Number | 50 | 50 | 50 | 150 |
| Men | 42 | 46 | 43 | 131 (87%) |
| Age (years) | 61.9 (7.5) | 62.3 (8.3) | 62.4 (10.2) | 62.3 (8.7) |
| Weight (kg) | 81.5 (12.7) | 85.1 (13.1) | 82.6 (19.5) | 83.3 (15.3) |
| Height (cm) | 173 (9) | 174 (10) | 172 (10) | 173 (9) |
| Body mass index (kg/m2) | 27.3 (3.6) | 28.4 (4.8) | 27.7 (5.6) | 27.9 (4.6) |
| Body surface area (m2) | 1.97 (0.18) | 2.01 (0.19) | 1.98 (0.26) | 2.0 (0.21) |
| Elective/urgent surgery | 36/12 | 38/10 | 32/14 | 106/36 |
| Aspirin (yes/no) | 12/34 | 12/35 | 13/32 | 37/101 |
| Number of grafts | 2.8 (0.6) | 2.8 (0.6) | 2.7 (0.6) | 2.8 (0.6) |
| CPB time (min) | 64 (17) | 65 (15) | 67 (23) | 65 (18) |