Summary of significant, recent trial data relevant to the question of treating patients with ACS by PCI or CABG
| n PCI | Subset of patients with ACS | |||||||
|---|---|---|---|---|---|---|---|---|
| Dates | Number unstable | Number treated invasively | n CABG | Mortality (% at 1 year) | MI (% at 1 year) | Revascularisation (% at 1 year) | ||
| ACS, acute coronary syndrome; CABG, coronary artery bypass grafting; IHD, ischaemic heart disease; MI, myocardial infarction; PCI, percutaneous coronary intervention. | ||||||||
| Trials of invasive v conservative strategy for ACS | ||||||||
| FRISC II | 1996–98 | 2457 | 1222 | 530 | PCI | ~1 | ~15 | 14.3 |
| 425 | CABG | ~3 | ~9 | 1.6 | ||||
| TACTICS-TIMI 18 | 1997–99 | 2220 | 1114 | 459 | PCI | 8.7 | 14.8 | |
| 220 | CABG | 9.1 | 6.9 | |||||
| RITA 3 | 1997–2001 | 1810 | 895 | 311 | PCI | 4.6 | 3.8 | ? |
| 184 | CABG | |||||||
| Trials of PCI v CABG for IHD | ||||||||
| ERACI II | 1996–98 | 411 | 450 | 207 | PCI | 0.9 | 0.9 | 16.8 |
| 204 | CABG | 5.7 | 5.7 | 4.8 | ||||
| ARTS | 1997–99 | 450 | 450 | 226 | PCI | 2.7 | 5.8 | 16.9 |
| 224 | CABG | 2.2 | 5.8 | 3.6 | ||||
| SoS | 1996–99 | 451 | 451 | 210 | PCI | ? | ? | ? |
| 241 | CABG | |||||||