Clinical and laboratory characteristics of heterozygous familial hypercholesterolaemia (FH) and normal women
| FH women | Normal women | p Value | |
|---|---|---|---|
| Data for age and cholesterol concentrations presented as mean (SD). | |||
| HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; VLDL-C, very low density lipoprotein cholesterol. | |||
| n | 27 | 71 | – |
| Age (years) | 40 (18) | 47 (8) | 0.01 |
| High blood pressure (%) | 14.8 | 11.3 | ns |
| Smokers and former smokers (%) | 14.8 | 40.8 | 0.017 |
| Obesity (%) | 14.8 | 12.7 | ns |
| Diabetes (%) | 0 | 1.4 | ns |
| Total cholesterol (mmol/l) | 9.64 (3.91) | 4.95 (0.9) | <0.0001 |
| LDL-C (mmol/l) | 7.62 (3.82) | 2.97 (0.74) | <0.0001 |
| HDL-C (mmol/l) | 1.34 (0.25) | 1.47 (0.33) | ns |
| VLDL-C (mmol/l) | 0.27 (0.1) | 0.22 (0.01) | 0.03 |
| Triglycerides (mmol/l) | 1.34 (0.53) | 1.12 (0.49) | 0.03 |