Table 1

Polymorphisms observed in KCNQ1

Exon	Polymorphism	Allele frequency (%)
The polymorphisms are numbered based on the start codon using the cDNA sequence NM 000218. Lower case letters refer to intronic bases and are located with respect to the corresponding intron-exon boundaries (5’ or 3’ +/− number of base pairs). Upper case letters refer to exonic bases. None of the observed polymorphisms changed amino acid sense.
1	gg insertion 3’+81	3.9
	G174A, T58T	1.06
1A	c->t 5’ UTR -129	0.7
2	C228T, Y76Y	0.7
5	c->t 3’+8	0.35
10	c->t 5’-14	0.35
11	t->c 3’+14	9.6
12	G1353A, S452S	20.2
	g->a 3’+36	37.6
13	t->c 3’+43	22.3
15	G1515A, T505T	0.35
	C1701T, Y567Y	22.7