Clinical characteristics of the study population
| All patients | T allele carriers | CC genotype | p Value* | |
|---|---|---|---|---|
| *p Values compare T allele carriers to CC genotype. | ||||
| Hypercholesterolaemia was defined as: total cholesterol >240 mg/dl; diabetes as fasting glycaemia >126 mg/dl on at least two occasions; hypertension as blood pressure >140/90 mm Hg; smoking as a smoker of > 1 cigarette per day at the time of admission; family history as documented acute coronary syndrome before 60 years of age in at least one first degree relative. | ||||
| All | 117 (100%) | 68 (58.1%) | 49 (41.9%) | |
| Mean age (years) | 54.3 (8.2) | 55.1 (7.5) | 52.9 (1.3) | 0.27 |
| Females | 16 (13.7%) | 10 (14.7%) | 6 (12.2%) | 0.79 |
| Smokers | 71 (60.7%) | 36 (52.9%) | 35 (71.4%) | 0.06 |
| Systemic hypertension | 64 (54.7%) | 37 (54.4%) | 27(55.1%) | 1 |
| Hypercholesterolemia | 52 (44.4%) | 31 (45.6%) | 21 (42.9%) | 0.85 |
| Family history of ischaemic heart disease | 44 (37.6%) | 23 (33.8%) | 21 (42.9%) | 0.34 |
| Diabetes mellitus | 19 (16.2%) | 13 (19.1%) | 6 (12.2%) | 0.32 |
| Mean left ventricular ejection fraction | 50.1% (10.2) | 49.4% (10.4) | 51.1% (9.9) | 0.42 |
| Percutaneous coronary interventions | 30 (25.6%) | 17 (25.0%) | 13 (26.5%) | 1 |
| Coronary artery bypass grafting | 12 (10.3%) | 8 (11.8%) | 4 (8.2%) | 0.76 |
| Coronary angiography | 90 (100%) | 54 (79.4%) | 36 (73.5%) | |
| Single vessel disease | 34 (37.8%) | 23 (42.6%) | 11 (30.6%) | 0.28 |
| Multi vessel disease | 51 (56.7%) | 29 (53.7%) | 22 (61.1%) | 0.82 |