High risk features and markers of patients with non-ST elevation ACS
| CABG, coronary artery bypass graft; CRP, C reactive protein, IL, interleukin; LV, left ventricular; MI, myocardial infarction; NT pro BNP, N terminal pro brain type natriuretic peptide. |
| ▸ High risk features in the early triage of patients |
| Continued or recurrent ischaemia at rest |
| Ischaemia complicated by cardiac failure, arrhythmia or mechanical complications |
| Ischaemia with ST segment depression and/or troponin elevation |
| Dynamic ST changes |
| ▸ Markers of pre-existing longer term risk |
| Age |
| Prior MI, CABG, diabetes, congestive heart failure, or hypertension |
| Biological markers of renal dysfunction (raised creatinine or reduced creatinine clearance) |
| Elevated inflammatory markers (high sensitivity CRP, IL-6, CD40L) |
| ▸ LV dysfunction |
| Invasive or non-invasive markers of LV dysfunction or mechanical complication |
| Biological markers of LV dysfunction (NT pro BNP) |
| Extent of coronary artery disease on angiography |