Haemodynamic variables and coronary vasoreactivity
| Increased CRP | Normal CRP | |||
|---|---|---|---|---|
| Value | % change | Value | % change | |
| Data are mean (SEM). | ||||
| *p<0.01 v others; †p<0.01 v baseline; ‡p<0.01 v normal CRP. | ||||
| Baseline mean blood pressure (mm Hg) | 112 (4) | 107 (3) | ||
| Baseline heart rate (beats/min) | 68 (3) | 67 (2) | ||
| Coronary diameter (mm) | ||||
| Baseline | 3.12 (0.14) | 0 | 3.12 (0.10) | 0 |
| Acetylcholine 3 μg/min | 3.13 (0.15) | −0.1 (1.9) | 3.15 (0.10) | 1.1 (1.3) |
| Acetylcholine 30 μg/min | 3.03 (0.16) | −3.3 (2.5) | 3.08 (0.11) | −1.2 (1.8) |
| Glyceryl trinitrate | 3.54 (0.13)* | 15.3 (3.4)* | 3.51 (0.09)* | 13.0 (2.4)* |
| Coronary blood flow (ml/min) | ||||
| Baseline | 68.5 (8.6) | 0 | 79.0 (6.0) | 0 |
| Acetylcholine 3 μg/min | 93.5 (15.3)† | 34.0 (11.7)† | 118.1 (10.6)† | 50.6 (8.2)† |
| Acetylcholine 30 μg/min | 107.8 (21.7)*‡ | 54.9 (18.8)*‡ | 187.7 (15.1)* | 139.4 (13.1)* |
| Coronary flow reserve | 3.12 (0.21) | 3.28 (0.15) | ||