Univariate analysis for mortality and clinical events in patients with chronic Chagas disease
| Variable | Survival | Death | No clinical event | Clinical event | Total |
|---|---|---|---|---|---|
| Data are mean (SD) or proportion. | |||||
| Evaluation by χ2 test: clinical events, change in clinical group, EARD (ECG abnormalities related to the disease), NEARD (new ECG abnormalities related to the disease), systolic dysfunction, and segmental lesions. Evaluated by unpaired Student’s t test: LASD (left atrial systolic dimension), LVDD (left ventricular diastolic dimension), LVSD (left ventricular systolic dimension), PWT (diastolic posterior wall thickness), RVDD (right ventricular diastolic dimension), and SWT (diastolic septal wall thickness). | |||||
| *p<0.01; **p<0.05; ***p<0.0001 compared with alive group; †p<0.05; ††p<0.0001 compared with patients without clinical events. | |||||
| Age at admission (years) | 43.39 (11.11) | 49.12 (13.11)** | 42.65 (11.21) | 47.50 (10.13)†† | 849 |
| EARD | 304/833 (36%) | 14/16 (87%)*** | 220/699 (31%) | 98/150 (65%)†† | 849 |
| NEARD | 112/833 (13%) | 9/16 (56%)*** | – | – | 849 |
| Change in clinical group | 68/833 (8%) | 15/16 (94%)*** | – | – | 849 |
| RVDD (cm) | 1.85 (0.55) | 2.12 (0.55) | 1.83 (0.52) | 1.97 (0.65)† | 753 |
| LVDD (cm) | 4.96 (0.62) | 5.99 (0.68)*** | 4.88 (0.54) | 5.44 (0.83)†† | 849 |
| LVSD (cm) | 3.06 (0.72) | 4.71 (0.90)*** | 2.98 (0.62) | 3.64 (1.03)†† | 840 |
| LASD (cm) | 3.44 (0.57) | 3.82 (0.82) | 3.39 (0.54) | 3.74 (0.69)†† | 817 |
| Radius: thickness ratio | 2.88 (0.70) | 3.97 (1.50)* | 2.83 (0.65) | 3.24 (1.02)†† | 823 |
| PWT (cm) | 0.89 (0.22) | 0.81 (0.18) | 0.89 (0.21) | 0.89 (0.27) | 825 |
| SWT cm) | 0.98 (0.24) | 0.95 (0.20) | 0.98 (0.23) | 0.99 (0.27) | 820 |
| Systolic dysfunction | 60/832 (7%) | 8/16 (50%)*** | 30/698 (4%) | 38/150 (25%)†† | 848 |
| Segmental lesions | 197/833 (24%) | 14/16 (87%)*** | 141/699 (20%) | 70/150(47%)†† | 849 |
| EF (%) | 0.67 (0.11) | 0.42 (0.17)*** | 0.68 (0.10) | 0.60 (0.16)†† | 840 |