Doppler echocardiographic diastolic indices of transmitral flow in the oestradiol and placebo groups at baseline, 90 minutes, and 12 weeks
| Variable | Time point | Oestradiol | Placebo | p Value |
|---|---|---|---|---|
| The values are expressed as mean (SD). | ||||
| *p<0.05 (T1 v T3) in the same group. | ||||
| †p<0.001 (T1 v T3) in the same group. | ||||
| DTE, deceleration time of mitral E wave; E/A, the ratio between the peak velocity of mitral E and A wave; IVRT, isovolumic relaxation time; Vel A, peak velocity of mitral A wave; Vel E, peak velocity of mitral E wave. | ||||
| Vel E (cm/s) | Baseline (T1) | 66 (19) | 63 (11) | NS |
| 90 minutes (T2) | 68 (20) | 61 (13) | NS | |
| 12 weeks (T3) | 74 (22) | 61 (16) | NS | |
| Vel A (cm/s) | Baseline (T1) | 81 (21) | 79 (14) | NS |
| 90 minutes (T2) | 81 (21) | 76 (11) | NS | |
| 12 weeks (T3) | 75 (23)* | 73 (13)* | NS | |
| E/A ratio | Baseline (T1) | 0.8 (0.2) | 0.8 (0.1) | NS |
| 90 minutes (T2) | 0.9 (0.2) | 0.8 (0.1) | NS | |
| 12 weeks (T3) | 1.0 (0.2)† | 0.8 (0.2) | 0.04 | |
| DTE (ms) | Baseline (T1) | 260 (42) | 254 (22) | NS |
| 90 minutes (T2) | 248 (40) | 245 (20) | NS | |
| 12 weeks (T3) | 238 (20)* | 274 (42)* | 0.01 | |
| IVRT (ms) | Baseline (T1) | 127 (23) | 121 (15) | NS |
| 90 minutes (T2) | 121 (17) | 120 (16) | NS | |
| 12 weeks (T3) | 106 (16)† | 121 (16) | 0.01 | |