Doppler echocardiographic diastolic variables of pulmonary venous flow, left ventricular mass index per unit body surface area, and size of left atrium in the oestradiol and placebo groups at the three time points
| Variable | Time point | Oestradiol | Placebo | p Value |
|---|---|---|---|---|
| The values are expressed as mean (SD). | ||||
| *p = 0.02 (T1 v T2) in the same group. | ||||
| †p = 0.001 (T1 v T3) in the same group. | ||||
| D, peak velocity of pulmonary diastolic wave; LA, left atrium; LVM/BSA, left ventricular mass indexed by body surface area; S, peak velocity of pulmonary systolic wave; S/D ratio, the ratio between the peak velocity of pulmonary S and D wave; Vel a, peak velocity of pulmonary a wave. | ||||
| S (cm/s) | Baseline (T1) | 64 (16) | 59 (12) | NS |
| 90 minutes (T2) | 61 (13) | 59 (11) | NS | |
| 12 weeks (T3) | 61 (10) | 60 (7) | NS | |
| D (cm/s) | Baseline (T1) | 41 (10) | 37 (7) | NS |
| 90 minutes (T2) | 39 (8) | 37 (6) | NS | |
| 12 weeks (T3) | 40 (8) | 41 (12) | NS | |
| S/D ratio | Baseline (T1) | 1.6 (0.3) | 1.6 (0.2) | NS |
| 90 minutes (T2) | 1.6 (0.3) | 1.6 (0.2) | NS | |
| 12 weeks (T3) | 1.5 (0.2) | 1.5 (0.2) | NS | |
| Vel a (cm/s) | Baseline (T1) | 31 (4) | 30 (3) | NS |
| 90 minutes (T2) | 29 (3)* | 28 (4)* | NS | |
| 12 weeks (T3) | 27 (3)† | 29 (2)† | NS | |
| LVM/BSA (g/m2) | Baseline (T1) | 113 (29) | 107 (28) | NS |
| 90 minutes (T2) | 109 (29) | 108 (26) | NS | |
| 12 weeks (T3) | 103 (20) | 113 (28) | NS | |
| LA size (cm) | Baseline (T1) | 3.7 (0.4) | 3.6 (0.4) | NS |
| 90 minutes (T2) | 3.7 (0.4) | 3.6 (0.4) | NS | |
| 12 weeks (T3) | 3.7 (0.4) | 3.6 (0.3) | NS | |