Type | First choice | If refractory |
---|---|---|
Check liver function before and after one month on statin. | ||
Check renal function before and after one month on fibrate. | ||
Check serum creatine kinase (CK) only if myalgia occurs during statin or fibrate treatment. | ||
Hypercholesterolaemia | Statin | Add cholesterol absorption inhibitor, bile acid sequestrant, or nicotinic acid |
Hypertriglyceridaemia | Fibrate | Add nicotinic acid or ω3 fatty acids |
Mixed hyperlipidaemia | Statin | Substitute or add fibrate (not gemfibrozil + statin) |
Low HDL cholesterol | Statin | Substitute or add fibrate or nicotinic acid |