Biological data (paired t test with confidence intervals)
| Variable | Placebo | Testosterone | Analysis of difference between groups | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | 4 weeks | p Value | Baseline | 4 weeks | p Value | Difference with testosterone | 95% CI | p Value | |
| *p < 0.05. | |||||||||
| CI, confidence interval; HDL, high density lipoprotein cholesterol; LDL, low density lipoprotein cholesterol. | |||||||||
| Time to 1 mm ST depression (s) | 345 (149) | 352 (150) | 0.492 | 318 (99) | 399 (84) | <0.0001* | 74 (54) | 35.4 to 112.6 | 0.002* |
| Serum TNF (pg/ml) | 2.39 (1.1) | 3.44 (2.3) | 0.04* | 4.13 (2.8) | 2.9 (1.8) | 0.117 | −1.8 (2.4.) | −3.7 to 0.025 | 0.05* |
| Haemoglobin (g/l) | 148 (8.6) | 149 (8.9) | 0.81 | 147 (9.8) | 150 (8.6) | 0.02* | 0.29 (0.79) | −0.27 to 0.86 | 0.273 |
| Packed cell volume | 0.44 (0.03) | 0.44 (0.027) | 0.8 | 0.43 (0.028) | 0.44 (0.025) | 0.01* | 0.008 (0.02) | −0.001 to 0.025 | 0.343 |
| Total cholesterol (mmol/l) | 4.18 (0.89) | 4.3 (0.79) | 0.42 | 4.19 (0.59) | 3.92 (0.55) | 0.004* | −0.41 (0.54) | −0.8 to −0.02 | 0.04* |
| LDL (mmol/l) | 2.1 (0.58) | 2.0 (0.6) | 0.8 | 2.2 (0.7) | 1.96 (0.51) | 0.08 | −0.08 (0.4) | −0.41 to 0.25 | 0.35 |
| HDL (mmol/l) | 0.95 (0.23) | 0.9 (0.17) | 0.41 | 0.94 (0.14) | 0.92 (0.15) | 0.26 | 0.06 (0.21) | −0.12 to 0.23 | 0.4 |
| Triglyceride (mmol/l) | 2.87 (1.94) | 2.94 (1.48) | 0.954 | 2.31 (1.25) | 2.29 (0.89) | 0.116 | −0.9 (1.7) | −2.2 to 0.41 | 0.15 |
| Total testosterone (nmol/l) | 5.55 (2.36) | 5.5 (2.53) | 0.94 | 4.39 (1.24) | 9.19 (5.09) | 0.02 | 4.75 (6.6) | 0.007 to 9.49 | 0.05* |
| Bioavailable testosterone (nmol/l) | 3.63 (1.8) | 3.5 (1.7) | 0.85 | 2.18 (1.1) | 6.07 (3.3) | 0.007 | 3.8 (4.47) | 0.61 to 7.0 | 0.025* |