Number of patients | Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|---|
RR (95% CI) | p Value | RR (95% CI) | p Value | ||
Intention to treat analysis. A patient was classified into a given drug group when the medication was given on day 0 and continued until at least day 30. | |||||
Atrioventricular (AV) node slowing drugs: β blockers, verapamil, digitalis. Other antihypertensive drugs: β blocker, dihydropyridine-type calcium antagonists, moxonidine, clonidine. | |||||
ACE, angiotensin converting enzyme; ARB: angiotensin II receptor blockers. | |||||
Class I drugs | 56 (29%) | 1.96 (1.33 to 2.87) | <0.01 | 1.66 (1.06 to 2.60) | 0.03 |
Class III drugs | 74 (38%) | 0.86 (0.58 to 1.26) | 0.43 | 0.76 (0.50 to 1.19) | 0.23 |
AV node slowing drugs | 85 (43%) | 1.22 (0.85 to 1.78) | 0.29 | 0.97 (0.66 to 1.44) | 0.89 |
ACE inhibitors/ARB | 46 (23%) | 0.62 (0.37 to 0.99) | 0.04 | 0.55 (0.31 to 0.97) | 0.04 |
Diuretics | 27 (14%) | 0.34 (0.16 to 0.70) | <0.01 | 0.28 (0.13 to 0.63) | <0.01 |
Other antihypertensive drugs | 85 (43%) | 1.01 (0.73 to 1.64) | 0.67 | 1.00 (0.70 to 1.58) | 0.83 |