Clinical characteristics
| Diabetic patients (n = 100) | Non-diabetic patients (n = 100) | p Value | |
|---|---|---|---|
| Data are mean (SD) or number (%) of CFI measurements. | |||
| ACE, angiotensin converting enzyme; AT II, angiotensin II; CAD, coronary artery disease; HDL, high density lipoprotein; LDL, low density lipoprotein; LVEDP, left ventricular end diastolic pressure; LVEF, left ventricular ejection fraction; NS, not significant. | |||
| Men | 78 (78%) | 78 (78%) | NS |
| Age (years) | 64 (9) | 64 (9) | NS |
| Body mass index (kg/m2) | 28.4 (3.8) | 26.2 (3.8) | 0.0002 |
| Mean aortic pressure (mm Hg) | 91 (11) | 91 (14) | NS |
| Heart rate (beats/min) | 72 (13) | 70 (13) | NS |
| LVEF (%) | 64 (11) | 63 (12) | NS |
| LVEDP (mm Hg) | 12.9 (6.5) | 12.3 (5.0) | NS |
| Duration of angina pectoris (months) | 21 (42) | 20 (41) | NS |
| Cardiovascular risk factors | NS | ||
| Systemic hypertension | 73 (73%) | 69 (69%) | NS |
| Smoking | 36 (36%) | 38 (38%) | NS |
| Hypercholesterolaemia | 52 (52%) | 54 (54%) | NS |
| Family history of CAD | 31 (31%) | 41 (41%) | NS |
| Cardiovascular medication | NS | ||
| Aspirin | 86 (86%) | 84 (84%) | NS |
| β Blockers | 64 (64%) | 69 (69%) | NS |
| Nitrates | 39 (39%) | 37 (37%) | NS |
| Statins | 39 (39%) | 42 (42%) | NS |
| ACE inhibitors | 35 (35%) | 25 (25%) | NS |
| AT II receptor antagonists | 8 (8%) | 4 (4%) | NS |
| Calcium antagonists | 23 (23%) | 15 (15%) | NS |
| Diuretics | 29 (29%) | 20 (20%) | NS |
| Blood chemistry | NS | ||
| Total cholesterol (mmol/l) | 5.3 (1.2) | 5.3 (1.0) | NS |
| HDL cholesterol (mmol/l) | 1.1 (0.4) | 1.2 (0.3) | NS |
| LDL cholesterol (mmol/l) | 3.2 (1.0) | 3.4 (0.9) | NS |
| Total cholesterol:HDL cholesterol | 4.8 (1.7) | 4.7 (1.6) | NS |
| Triglycerides (mmol/l) | 2.2 (1.7) | 2.1 (1.7) | NS |
| Fasting blood glucose (mmol/l) | 8.9 (3.3) | 6.0 (0.9) | <0.0001 |
| Haemoglobin A1c (%) | 7.2 (2.4) (n = 15) | 5.9 (0.4) (n = 12) | 0.05 |