Table 3

Comparisons between patients with CAD and healthy controls on haemostatic indices

	Overall CAD (n = 53)		Controls (n = 19)	Intergroup_Before p value*	CAD_{Before − After} p value†	Controls_{Before − After} p value†	Group × exercise effects‡
	Overall CAD (n = 53)		Controls (n = 19)	Intergroup_Before p value*	CAD_{Before − After} p value†	Controls_{Before − After} p value†	F(1, 70)	p Value
Data are mean (SD) or median (interquartile range).
*Unpaired Student’s t or Mann-Whitney U test; †paired Student’s t or Wilcoxon test; ‡two way analysis of variance with repeated measures of the exercise effect in group by exercise interactions.
PV, plasma viscosity; sP-sel, soluble P-selectin; vWf, von Willebrand factor.
After applying correction for contraction of plasma volume
vWf_before (IU/dl)	162 (45)		122 (17)	<0.001
vWf_after (IU/dl)	170 (48)		124 (17)		0.018	0.23	16.4	0.001
Fibrinogen_before (g/l)	2.9 (0.7)		2.5 (0.7)	0.041
Fibrinogen_after (g/l)	3.1 (0.7)		2.7 90.7)		<0.001	0.008	4.6	0.035
D-dimer_before (mg/l)	0.20 (0.10–0.30)		0.20 (0.10–0.30)	0.90
D-dimer_after (mg/l)	0.21 (0.12–0.31)		0.20 (0.10–0.35)		0.006	0.62	0.10	0.75
sP-sel_before (ng/ml)	78 (68–88)		67 (59–85)	0.033
sP-sel_after (ng/ml)	75 (66–92)		69 (62–76)		0.50	0.96	4.0	0.049
PV_before (mPa·s)	1.63 (0.12)		1.60 (0.08)	0.29
PV_after (mPa·s)	1.71 (0.14)		1.64 (0.08)		<0.001	0.001	2.9	0.09
Before applying correction for contraction of plasma volume
vWf_before (IU/dl)		162 (45)	122 (17)	<0.001
vWf_after (IU/dl)		178 (49)	126 (17)		<0.001	0.016	18.2	0.001
Fibrinogen_before (g/l)		2.9 (0.7)	2.5 (0.7)	0.041
Fibrinogen_after(g/l)		3.2 (0.7)	2.7 (0.7)		<0.001	0.001	5.8	0.019
D-dimer_before (mg/l)		0.20 (0.10–0.30)	0.20 (0.10–0.30)	0.90
D-Dimer_after (mg/l)		0.21 (0.12–0.31)	0.20 (0.10–0.35)		<0.001	0.43	0.16	0.70
sP-sel_before (ng/ml)		78 (68–88)	67 (59–85)	0.033
sP-sel_after (ng/ml)		79 (68–93)	72 (63–78)		0.19	0.24	1.5	0.29
PV_before (mPa·s)		1.63 (0.12)	1.60 (0.08)	0.29
PV_after (mPa·s)		1.71 (0.14)	1.64 (0.08)		<0.001	0.001	2.9	0.09