Haemodynamic data during and after withdrawal of treatment with angiotensin converting enzyme (ACE) inhibitor
| Treatment with ACE | After ACE withdrawal | p Value* | Minimum sample size for significance† | |
|---|---|---|---|---|
| Data presented as mean (IQR). | ||||
| *Exact Wilcoxon paired signed rank test; †calculated with parametric significance tests assuming normally distributed data (significance can be reached with a smaller sample when non-parametric exact tests are used). | ||||
| LV, left ventricular. | ||||
| Heart rate (beats/min) | 68 (29) | 70 (31) | 0.2 | 107 |
| Systolic blood pressure (mm Hg) | 140 (18) | 159 (12) | 0.02 | 71 |
| Diastolic blood pressure (mm Hg) | 80 (10) | 80 (10) | 0.5 | Infinite |
| Stroke volume (ml) | 56 (19) | 57 (35) | 0.5 | 356 |
| Cardiac output (l/min) | 3.7 (2.6) | 4.0 (1.6) | 0.4 | 860 |
| Systemic vascular resistance (dyn·s·cm−5) | 2.290 (1.059) | 2.153 (1.251) | 0.8 | 19016 |
| Mean pressure gradient (mm Hg) | 34 (15) | 28 (18) | 0.037 | 16 |
| Aortic valve area (cm2) | 0.66 (0.39) | 0.69 (0.34) | 0.7 | 2676 |
| LV end systolic wall stress (kdyn/cm2) | 14.0 (8.7) | 13.5 (8.6) | 0.3 | 190 |