Echocardiographic and cardiopulmonary exercise testing parameters in patients with hypertrophic cardiomyopathy (HCM) and in strength and endurance athletes
| Parameter | HCM (n = 27) | Strength (n = 19) | Endurance (n = 20) | p Value |
|---|---|---|---|---|
| *Significantly different from strength and endurance athletes; †significantly less than in endurance athletes; ‡significantly different from patients with HCM and strength athletes. | ||||
| AT, anaerobic threshold; AT%, percentage of predicted anaerobic threshold; LVEDD, left ventricular end diastolic diameter; LVWT, left ventricular wall thickness; NS, not significant; O2P, oxygen pulse at peak exercise; pVo2, peak oxygen consumption; pVo2%, percentage of predicted peak oxygen consumption; VE, minute ventilation; VCo2, carbon dioxide production; Vo2, oxygen consumption; WR, work rate. | ||||
| Age (years) | 19.90 (6.27) | 22.60 (3.89) | 22.00 (3.24) | NS |
| Weight (kg) | 75.77 (13.54) | 83.74 (13.37) | 80.45 (7.38) | NS |
| LVWT (mm) | 18.64 (5.54)* | 10.74 (1.40) | 10.10 (0.91) | <0.05 |
| Range | 13–35 | 9–13 | 9–12 | |
| LVEDD (mm) | 45.24 (4.81)* | 50.42 (2.87)† | 55.68 (3.23) | <0.05 |
| Range | 36–54 | 44–58 | 46–59 | |
| pVo2 (ml/kg/min) | 33.43 (6.84) | 31.51 (2.75) | 58.09 (4.59)‡ | <0.001 |
| pVo2% | 77.70 (12.25) | 73.89 (6.70) | 136.40 (11.51)‡ | <0.001 |
| AT (l/min) | 1.21 (0.26) | 1.18 (0.22) | 2.54 (0.41)‡ | <0.001 |
| AT% | 38.11 (8.39) | 34.11 (5.39) | 74.55 (10.99)‡ | <0.001 |
| O2P (ml/beat) | 13.93 (2.43) | 14.97 (1.73) | 25.35 (2.68)‡ | <0.001 |
| ΔVo2/ΔWR (ml/min/W) | 9.58 (0.93) | 8.96 (1.03) | 9.21 (0.87) | NS |
| VE/VCo2 slope | 27.38 (3.74) | 25.65 (1.76) | 22.36 (1.84)‡ | <0.001 |