Significant multivariable risk adjusted predictors of six month mortality and MACE after acute coronary syndrome
| Adjusted OR for death (95% CI) | p Value | Adjusted OR for MACE (95% CI) | p Value | |
|---|---|---|---|---|
| c-index for the mortality model was 0.80; c-index for the MACE model was 0.72. | ||||
| CI, confidence interval; OR, odds ratio. | ||||
| Age | 1.04 (1.02 to 1.06) | <0.001 | 1.03 (1.02 to 1.04) | <0.01 |
| Positive biomarker | 1.75 (1.11 to 2.75) | <0.001 | 1.76 (1.23 to 2.53) | <0.01 |
| Diabetes mellitus | 1.42 (0.95 to 2.09) | 0.08 | 1.29 (0.95 to 1.77) | 0.10 |
| Renal insufficiency | 2.21 (1.42 to 3.44) | <0.001 | 2.13 (1.46 to 3.10) | <0.001 |
| Heart failure at presentation | 3.88 (2.61 to 5.76) | <0.001 | 2.79 (1.99 to 3.84) | <0.001 |
| Clopidogrel | 0.48 (0.26 to 0.89) | 0.01 | 0.65 (0.39 to 1.07) | 0.09 |
| CYP3A4 statin | 0.43 (0.27 to 0.71) | 0.009 | 0.55 (0.36 to 0.83) | 0.004 |
| CYP3A4 statin + clopidogrel | 0.36 (0.23 to 0.60) | <0.001 | 0.53 (0.36 to 0.79) | 0.001 |
| Non-CYP3A4 statin | 0.22 (0.08 to 0.59) | 0.002 | 0.56 (0.28 to 1.08) | 0.08 |
| Non-CYP3A4 statin + clopidogrel | 0.22 (0.06 to 0.76) | 0.016 | 0.68 (0.34 to 1.67) | 0.28 |