Comparison of outcomes of clinical trials of infusion of autologous bone marrow derived progenitor cells following acute myocardial infarction.
| Study | LVEF method | No days after PPCI | n | LVEF pre | LVEF post | dEF | p Value |
|---|---|---|---|---|---|---|---|
| Adapted from Mathur and Martin37 with permission. | |||||||
| BMSC, bone marrow stem cell; LVEF, left ventricular ejection fraction; MRI, magnetic resonance imaging; PPCI, primary percutaneous coronary intervention. | |||||||
| Assmus et al34 | Ventriculography | 4.3 (1.5) | 20 Control | 51% (10) | 53.3%(7.9) | 2.3% | NS |
| 20 BMSC | 51.6% (9.6) | 60.1% (8.6) | 8.5% | 0.003 | |||
| Strauer et al35 | Ventriculography | 5.9 | 10 Control | 60% (7) | 64% (7) | 4.0% | NS |
| 10 BMSC | 57% (8) | 62% (10) | 5.0% | NS | |||
| Wollert et al36 | MRI | 4.8 (1.3) | 30 Control | 51.3% (9.3) | 52% (12.4) | 0.7% | NS |
| 30 BMSC | 50% (10) | 56.7% (12.5) | 6.7% | 0.0026 | |||