Description of study groups
| Group A: CAD | Group B: controls | p Value | |
|---|---|---|---|
| Data are mean (SD) or number (%). | |||
| BP, blood pressure; CAD, coronary artery disease. | |||
| Number | 26 | 12 | |
| Age (years) | 58.9 (8.1) | 56.1 (8.8) | 0.341 |
| Single vessel disease | 9 (35%) | 0% | 0.036 |
| Double vessel disease | 9 (35%) | 0% | 0.036 |
| Triple vessel disease | 8 (30%) | 0% | 0.039 |
| Resting heart rate (beats/min) | 77 (13) | 80 (11) | 0.493 |
| Resting systolic BP (mm Hg) | 147 (15) | 137 (14) | 0.059 |
| Resting diastolic BP (mm Hg) | 91 (10) | 89 (6) | 0.527 |
| Exercise duration (s) | 379 (114) | 474 (143) | 0.034 |
| ST depression (mm) | −2.4 (1.3) | −0.2 (0.1) | <0.001 |
| Peak heart rate (beats/min) | 140 (20) | 161 (9) | <0.001 |
| Peak systolic BP (mm Hg) | 184 (14) | 189 (11) | 0.244 |
| Peak diastolic BP (mm Hg) | 97 (7) | 97 (7) | 0.882 |
| Peak double product (×103 mm Hg/min) | 25.9 (5.0) | 30.2 (2.0) | 0.001 |
| Serum cholesterol (mmol/l) | 5.3 (1.2) | 5.6 (1.3) | 0.490 |
| Serum triglycerides (mmol/l) | 2.6 (1.7) | 2.0 (1.6) | 0.310 |
| Treated hypertension | 12 (46%) | 5 (42%) | 0.999 |
| Current/recent smoker (within 3 months) | 11 (42%) | 2 (17%) | 0.158 |
| Diabetes | 4 (15%) | 5 (42%) | 0.108 |
| β Blocker | 18 (69%) | 2 (17%) | 0.004 |
| Calcium channel blocker | 18 (69%) | 1 (8%) | 0.001 |
| Nitrate | 13 (50%) | 0 (0%) | 0.003 |
| Aspirin | 23 (88%) | 4 (33%) | 0.001 |