Characteristics of cases and controls
| Cases (n = 63512) | Controls (n = 378886) | Crude OR(95% CI) | |
|---|---|---|---|
| *Control age is at matched case patient’s first myocardial infarction (MI) date. | |||
| CI, confidence interval; OR, odds ratio. | |||
| Men | 38604 (60.78%) | 229843 (60.66%) | Matching variable |
| Age at first MI* (years) | |||
| <60.0 | 12149 (19.13%) | 72861 (19.23%) | Matching variable |
| 60.0–69.9 | 15321 (24.12%) | 92243 (24.35%) | Matching variable |
| 70.0–79.9 | 19793 (31.16%) | 119063 (31.42%) | Matching variable |
| ⩾80 | 16249 (25.58%) | 94719 (25.0%) | Matching variable |
| Smoking status | |||
| Never smoker | 24198 (38.1%) | 156510 (41.31%) | 1.00 |
| Former smoker | 4105 (6.46%) | 21159 (5.58%) | 1.31 (1.26 to 1.36) |
| Current smoker | 17133 (26.98%) | 69670 (18.39%) | 1.67 (1.63 to 1.71) |
| Missing data | 18076 (28.46%) | 131547 (34.72%) | 0.81 (0.79 to 0.83) |
| Body mass index (kg/m2) | |||
| Underweight (<18.5) | 474 (0.75%) | 3191 (0.84%) | 0.94 (0.85 to 1.04) |
| Normal (18.5–24.9) | 10448 (16.45%) | 67217 (17.74%) | 1.00 |
| Overweight (25.0–29.9) | 12247 (19.28%) | 65393 (17.26%) | 1.21 (1.18 to 1.25) |
| Obese (⩾30) | 5006 (7.88%) | 22019 (5.81%) | 1.48 (1.43 to 1.54) |
| Missing data | 35337 (55.64%) | 221066 (58.35%) | 0.99 (0.97 to 1.02) |
| Systolic blood pressure (mm Hg) | |||
| <133 | 10122 (15.94%) | 62539 (16.51%) | 1.00 |
| 134–147 | 11423 (17.99%) | 61153 (16.14%) | 1.19 (1.15 to 1.22) |
| 148–159 | 10547 (16.61%) | 52139 (13.76%) | 1.30 (1.27 to 1.35) |
| 160–250 | 15195 (23.92%) | 72244 (19.07%) | 1.35 (1.31 to 1.39) |
| Missing data | 16225 (25.55%) | 130811 (34.53%) | 0.70 (0.68 to 0.72) |
| Diastolic blood pressure (mm Hg) | |||
| <78 | 10801 (17.01%) | 60300 (15.92%) | 1.00 |
| 79–83 | 11370 (17.9%) | 64374 (16.99%) | 0.98 (0.96 to 1.01) |
| 84–89 | 9898 (15.58%) | 49777 (13.14%) | 1.13 (1.09 to 1.16) |
| 90–172 | 15216 (23.96%) | 73613 (19.43%) | 1.15 (1.12 to 1.18) |
| Missing data | 16227 (25.55%) | 130822 (34.53%) | 0.62 (0.60 to 0.63) |
| Drug prescribed before first MI | |||
| Antihypertensive drug | 2149 (3.38%) | 4738 (1.25%) | 2.93 (2.78 to 3.09) |
| Hyperlipidaemic drug | 9973 (15.70%) | 40155 (10.6%) | 1.62 (1.58 to 1.66) |
| Diabetes diagnosed | 8877 (13.98%) | 26395 (6.97%) | 2.19 (2.13 to 2.25) |