Antibiotic prophylaxis for IE during urological and digestive procedures: Administration of antibiotics respecting contraindications and usual conditions of use and surveillance
| Antibiotic | Dosage and route of administration | ||
|---|---|---|---|
| Before (in the hour before the procedure) | After (6 h hours later) | ||
| Paediatric dosage: amoxicillin 50 mg/kg iv before, 25 mg/kg orally 6 hours later; gentamicin 2 mg/kg (maximum 80 mg); vancomycin 20 mg/kg (maximum 1 g); teicoplanin: no official approval for antibiotic prophylaxis in children. | |||
| im, intramuscularly. | |||
| If antibiotic prophylaxis concerns a procedure for which the microorganism is a staphylococcus, pristinamycin should be used unless contraindicated. | |||
| No allergy to β lactams | Amoxicillin then | 2 g iv (infusion 30 min) | 1 g orally |
| gentamicin | 1.5 mg/kg iv (infusion 30 min) or im | No second dose | |
| Allergy to β lactams | Vancomycin or | 1 g iv (infusion ⩾60 min) | No second dose |
| teicoplanin then | 400 mg iv (bolus) | ||
| gentamicin | 1.5 mg/kg iv (infusion 30 min) or im | ||