Number | 331 | 990 | |
Age (years) | 70 (10) | 69 (9) | 0.3 |
Men | 226 (68%) | 716 (72%) | 0.2 |
Medical history | | | |
Prior cerebral ischaemia | 69 (21%) | 170 (17%) | 0.1 |
Hypertension | 217 (66%) | 529 (53%) | <0.001 |
Diabetes mellitus | 75 (23%) | 121 (12%) | <0.001 |
Peripheral vascular disease | 40 (12%) | 58 (6%) | <0.001 |
Prior MI | 89 (27%) | 72 (7%) | <0.001 |
Angina | 74 (22%) | 102 (10%) | <0.001 |
CABG | 62 (19%) | 98 (10%) | <0.001 |
Drug treatment at time of blood sampling | | |
ACE inhibitor | 218 (66%) | 197 (20%) | <0.001 |
Loop diuretic | 233 (70%) | 96 (10%) | <0.001 |
Warfarin | 232 (70%) | 381 (39%) | <0.001 |
Aspirin | 159 (48%) | 636 (64%) | <0.001 |
Smoking history (former + current) | 195 (58%) | 587 (59%) | 0.9 |
Systolic BP (mm Hg) | 136 (20) | 137 (20) | 0.4 |
Diastolic BP (mm Hg) | 76 (11) | 79 (10) | 0.001 |
LV dysfunction on two dimensional echocardiography | <0.001 |
Normal | 144 (44%) | 853 (86%) | |
Mild | 59 (18%) | 98 (10%) | |
Moderate | 58 (17%) | 33 (3%) | |
Severe | 70 (21%) | 6 (1%) | |
FS (%) | 28 (11) | 37 (8) | <0.001 |
Left atrial diameter (cm) | 5.0 (0.8) | 4.6 (0.7) | <0.001 |
Regurgitation | 251 (76%) | 598 (61%) | <0.001 |
vWf (IU/dl) | 154 (29) | 144 (31) | <0.001 |
sP-sel (ng/ml) | 32 (26–40) | 32 (25–41) | 0.7 |