(a) Death
| | | | | |
Age | 5 years | 1.17 (0.99 to 1.37) | 0.062 | 1.18 (1.08 to 1.30) | 0.0004 |
Haemoglobin | 20 g/l | 0.71 (0.52 to 0.96) | 0.024 | 0.69 (0.56 to 0.84) | 0.0003 |
Sodium | 5 mmol/l | 0.69 (0.48 to 0.98) | 0.035 | 0.82 (0.67 to 1.00) | 0.052 |
Neutrophils | 3×109/l | 1.10 (0.88 to 1.37) | 0.40 | 1.32 (1.19 to 1.47) | <0.0001 |
Urea | 5 mmol/l | 1.53 (1.25 to 1.87) | <0.0001 | 1.26 (1.14 to 1.38) | <0.0001 |
Spironolactone | Yes | 1.23 (0.56 to 2.72) | 0.61 | 1.87 (1.23 to 2.83) | 0.0032 |
Valve disease | Yes | 5.82 (2.43 to 14.0) | <0.0001 | 2.82 (1.10 to 7.24) | 0.032 |
Sex | Male | 2.44 (1.25 to 4.79) | 0.0094 | 0.96 (0.67 to 1.38) | 0.83 |
Covariate with significant interactions with systolic function |
COPD | Y | 11.6 (5.11 to 26.2) | <0.0001 | 1.64 (0.94 to 2.88) | 0.084 |
Tests for interaction: COPD p = 0.0006 |
(b) Death or hospital readmission for HF
|
Age | 5 years | 1.06 (0.92 to 1.22) | 0.39 | 1.12 (1.04 to 1.21) | 0.0030 |
Haemoglobin | 20 g/l | 0.83 (0.62 to 1.12) | 0.22 | 0.73 (0.61 to 0.87) | 0.0006 |
Sodium | 5 mmol/l | 0.60 (0.43 to 0.84) | 0.0030 | 0.92 (0.76 to 1.12) | 0.42 |
Neutrophils | 3×109/l | 1.17 (0.94 to 1.45) | 0.15 | 1.25 (1.12 to 1.40) | 0.0001 |
Spironolactone | Yes | 1.39 (0.65 to 2.94) | 0.40 | 1.96 (1.35 to 2.85) | 0.0004 |
Valve disease | Yes | 3.96 (1.67 to 9.38) | 0.0018 | 3.72 (1.68 to 8.24) | 0.0012 |
Covariates with significant interactions with systolic function: |
COPD | Yes | 9.86 (4.48 to 21.7) | <0.0001 | 1.61 (0.98 to 2.64) | 0.061 |
Sex | Male | 1.69 (0.91 to 3.15) | 0.038 | 0.84 (0.60 to 1.16) | 0.29 |
Urea | 5 mmol/l | 1.81 (1.46 to 2.24) | <0.0001 | 1.18 (1.07 to 1.29) | 0.0006 |
Tests for interaction: COPD p = 0.0002, sex p = 0.046, urea p = 0.0004 |