Population characteristics and biochemical variables in 400 Pakistani patients with and without metabolic syndrome defined by NCEP-ATP III modified for waist circumference
| Parameter | Metabolic syndrome (n = 176) | No metabolic syndrome (n = 224) |
|---|---|---|
| Data presented as mean (SD) or median (range). | ||
| *p = 0.02–0.05; **p = 0.01–0.001; ***p<0.001; †defining criteria. | ||
| CHD(+) | 53%*** | 48% |
| Gensini score | 11 (0–154)*** | 0 (0–224) |
| Age (years) | 51.4 (9.5)*** | 48.5 (9.5) |
| Men | 76%*** | 90% |
| Blood pressure (mm Hg)† | 139 (18)/87 (9)*** | 120 (13)/80 (9) |
| BMI (kg/m2) | 26.5 (3.7)*** | 24.5 (3.4) |
| Waist (cm)† | 90 (10)*** | 87 (9) |
| Total cholesterol (mmol/l) | 4.29 (1.13) | 4.25 (1.04) |
| Triglycerides (mmol/l)† | 1.48 (0.34–3.98)*** | 1.07 (0.08–3.34) |
| HDL (mmol/l)† | 0.75 (0.22)*** | 0.83 (0.23) |
| LDL (mmol/l) | 2.77 (1.06) | 2.86 (0.88) |
| Apolipoprotein A I (g/l) | 1.14 (0.20) | 1.13 (0.21) |
| Apolipoprotein B (g/l) | 0.96 (0.27)* | 0.89 (0.24) |
| HDL:apolipoprotein A I | 0.66 (0.15)*** | 0.73 (0.15) |
| LDL:apolipoprotein B | 2.88 (0.74)*** | 3.23 (0.60) |
| AST (IU/l) | 24 (9–109)* | 22 (7–171) |
| Lp(a) lipoprotein (g/l) | 0.05 (0.02–0.45) | 0.06 (0.02–0.65) |
| C reactive protein (mg/l) | 5 (0.3–175) | 6 (0.2–83) |
| Fibrinogen (g/l) | 2.20 (0.10–20.20) | 2.00 (0.10–10.60) |
| Sialic acid (mg/l) | 82 (13)*** | 77 (15) |
| Glucose (mmol/l)† | 7.3 (2.9)*** | 5.7 (1.5) |
| Insulin (pmol/l) | 45 (2–449)*** | 2 (2–424) |
| HOMA insulin resistance | 6.8 (0.4–164)*** | 0.6 (0.4–211) |
| Creatinine clearance (ml/min) | 91 (26–257) | 81 (15–276) |
| Homocysteine (μmol/l) | 18 (6–92) | 19 (7–56) |