mRNA expression of ANP, BNP, and collagens I and III in the non-infarcted myocardium after MI
| WT-MI | KO-MI | |||
|---|---|---|---|---|
| ACEI (−) | ACEI (+) | ACEI (−) | ACEI (+) | |
| Values are mean (SEM) (control = 1.0±0.0–0.1). | ||||
| ANP, atrial natriuretic peptide; BNP, brain natriuretic peptide. | ||||
| †p<0.05 v WT-MI ACEI (−); ††p<0.01 v WT-MI ACEI (−); §p<0.05 v WT-MI ACEI (+); §§p<0.01 v WT-MI ACEI (+); ¶p<0.05 v WT-KO ACEI (−); ¶¶p<0.01 v KO-MI ACEI (−). | ||||
| ANP | 15.0 (3.1) | 9.6 (0.9)† | 7.9 (1.9)†† | 3.1 (1.1)††§¶ |
| BNP | 8.6 (0.7) | 5.3 (0.2)†† | 5.9 (0.9)†† | 2.9 (0.2)††§¶¶ |
| Collagen I | 3.9 (0.4) | 2.7 (0.2)† | 2.5 (0.3)† | 1.4 (0.2)††§¶ |
| Collagen III | 4.6 (0.5) | 3.6 (0.1) | 3.1 (0.4)† | 1.9 (0.2)††§¶ |