Changes during low dose dobutamine stress echocardiography (LDSE) and their correlations with changes in mitral regurgitation fraction
| Variable | Changes during LDSE | Correlation between changes in variables and changes in RF | |||
|---|---|---|---|---|---|
| Baseline | Stress | p Value | r Value | p Value | |
| Data are presented as mean (SD). | |||||
| EF, ejection fraction; LDSE, low dose dobutamine stress echocardiography; LV, left ventricle; PM, papillary muscle; RF, regurgitant fraction; TL, tethering length; WMSI, wall motion score index. | |||||
| Haemodynamics | |||||
| Systolic arterial pressure (mm Hg) | 131 (28) | 150 (36) | <0.01 | 0.35 | 0.21 |
| Heart rate (beats/min) | 67 (15) | 81 (15) | <0.01 | 0.46 | 0.08 |
| Global LV volume and function | |||||
| End diastolic volume (ml) | 148 (49) | 147 (45) | NS | −0.05 | 0.86 |
| End systolic volume (ml) | 95 (40) | 84 (36) | <0.01 | −0.30 | 0.27 |
| EF (%) | 37 (7) | 45 (9) | <0.01 | 0.13 | 0.65 |
| Mitral valvar deformation | |||||
| Tenting area (cm2) | 1.0 (0.4) | 0.8 (0.4) | NS | 0.34 | 0.22 |
| Coaptation height (mm) | 5.9 (1.9) | 5.0 (2.3) | <0.05 | 0.68 | 0.006 |
| Systolic mitral annular area (cm2) | 6.4 (1.7) | 5.8 (1.4) | <0.05 | 0.06 | 0.84 |
| PM displacement | |||||
| Anterior TL (mm) | 34 (5) | 33 (4) | <0.05 | 0.36 | 0.18 |
| Posterior TL (mm) | 36 (6) | 34 (5) | NS | 0.62 | 0.01 |
| The sum of bilateral TL (mm) | 70 (8) | 67 (9) | <0.05 | 0.74 | 0.002 |
| WMSI | |||||
| The global LV | 1.9 (0.3) | 1.8 (0.3) | <0.01 | 0.44 | 0.10 |
| Anterolateral segments | 1.5 (0.4) | 1.3 (0.4) | NS | 0.19 | 0.49 |
| Inferoposterior segments | 1.8 (0.5) | 1.7 (0.5) | NS | 0.53 | 0.04 |
| Segments at the bilateral PM | 1.7 (0.3) | 1.5 (0.3) | <0.05 | 0.37 | 0.17 |