Table 2

Outcome of TPG before and after treatment with prostacyclin in five patients

	1	2	3	4	5	Mean (SD)	p Value*
Data are mean (SD).
*Before versus during treatment with prostacyclin.
LA, left atrial; PA, pulmonary artery.
Where LA pressure is stated this may also have been determined by pulmonary capillary wedge pressure assessment.
Duration of treatment before repeat catheterisation (days)	51	49	36	78	75	58 (18)
Before long term prostacyclin treatment
At catheterisation baseline
Mean PA pressure (mm Hg)	61	66	36	41	50	51 (12.7)
Mean LA pressure (mm Hg)	33	24	21	18	22	24 (5.7)
TPG (mm Hg)	28	42	15	23	28	27 (9.8)
CI (l/min/m²)		1.7	5.5	1.9	1.6
With acute vasodilator testing
Mean PA pressure (mm Hg)	43	58	31	34	42	42 (10.5)
Mean LA pressure (mm Hg)	33	28	15	16	23	23 (7.7)
TPG (mm Hg)	11	30	16	18	19	19 (6.8)
CI (l/min/m²)		2.3	5.5†	1.9	1.6
During long term prostacyclin treatment
At catheterisation baseline
Mean PA pressure (mm Hg)	48	50	29	34	42	41 (9.0)	<0.01
Mean LA pressure (mm Hg)	31	25	20	17	20	23 (5.5)	0.14
TPG (mm Hg)	17	25	9	17	22	17 (6.7)	0.01
CI (l/min/m²)		3.5	2.6	1.2	1.6
With acute vasodilator testing
Mean PA pressure (mm Hg)	44	38	26	33	38	35.8 (6.7)	0.19
Mean LA pressure (mm Hg)	43	22	19	20	17	24.2 (10.7)	0.722
TPG (mm Hg)	2	16	7	13	21	11 (7.5)	<0.05
CI (l/min/m²)		4.7	2.8	1.2	1.5