Table 3

 Prenatal and postnatal course of recipients with pulmonary stenosis

RecipientPostnatal cardiac diagnosisGA at LC (weeks)Recipient findingsDonorGA at delivery (weeks)Postnatal course
Fetal echocardiographyTRMRDVnegAIU PSUA velocityUA velocityEchocardiography
*Instantaneous pressure measured by the Bernoulli equation of echocardiography.
CHF, congestive heart failure; GA, gestational age; IU, intrauterine; LC, laser coagulation; MR, mitral valve regurgitation; PI, pulsatility index of the umbilical artery; Pmax, maximum pressure gradient; PS, pulmonary stenosis, UA, umbilical artery, UAEDF, umbilical artery end diastolic flow.
1Severe PS18+5Normal; week 20+5: normal; week 29: valvar PS, small valvar annulus+UAEDF normal, PI normalUAEDF normalNormal; fetal death 5 days after LC33+5Severe PS requiring balloon valvoplasty at ages 1 and 9 months; normal valve morphology; residual mild PS (32 mm Hg*)
2Severe PS20+3CHF+++UAEDF normal, PI normalUAEDF negativeNormal; fetal death 1 day after LC39+0Progression from moderate (Pmax 68 mm Hg*) to severe PS (Pmax 90 mm Hg*) within 4 months, no TR, small pulmonary annulus of 7 mm at 4 months, thickening of pulmonary valve leaflets; balloon valvoplasty at 4 months; residual mild PS of 30 mm Hg*
3Moderate PS19+0Mild CHF++UAEDF normal, PI normalUAEDF normalNormal35+1Postpartum systolic heart murmur; moderate PS (Pmax 40 mm Hg*), thickening of pulmonary valve leaflets
4Mild supravalvar stenosis19+4CHF+++UAEDF normal, PI normalUAEDF normalNormal35+4Mild increase in velocity within the pulmonary trunk (1.8 m/s)