Table 1 Clinical characteristics of the screened patient cohort (n = 135) divided into excluded patients, patients with latent obstruction and the non-obstructive patients
Excluded patients (n = 48)Latent obstruction (n = 54)Non-obstructive (n = 33)
Clinical parameters
Age (years)42.8 (11.8)40.6 (15.5)45.0 (12.4)
Males37 (77.1%)41 (75.9%)18 (54.5%)
Exertional chest pain26 (54.2%)25 (46.3%)15 (45.5%)
Atypical chest pain4 (8.3%)6 (11.1%)3 (9.1%)
NYHA I16 (33.0%)20 (37.0%)12 (36.4%)
NYHA II21 (43.8%)21 (38.9%)14 (42.4%)
NYHA III/IV7 (14.6%)6 (11.1%)6 (18.2%)
Palpitations11 (22.9%)17 (31.5%)11 (33.3%)
Presyncope/syncope26 (54.2%)30 (55.6%)15 (45.5%)
Echocardiographic parameters
Maximal left ventricular wall thickness (mm)21.5 (4.3)20.7 (5.4)21.6 (6.9)
Lest atrial diameter (mm)47.0 (6.3)44.8 (7.9)44.7 (6.9)
Left ventricular end diastolic diameter (mm)43.7 4.2)42.8 (4.8)43.9 (6.8)
Left ventricular end systolic diameter (mm)23.9 (4.5)24.0 (5.0)25.3 (5.8)
Fractional shortening45.5 (7.1%)44.4 (8.6%)42.6 (5.7%)
Resting incomplete SAM20 (41.7%)36 (66.7%)16 (48.5%)
Resting complete SAM28 (58.3%)5 (9.3%)0 (0%)
Mild mitral regurgitation at rest30 (22.2%)22 (16.3%)11 (8.1%)
Moderate mitral regurgitation at rest14 (10.4%)5 (3.7%)3 (2.2%)
Severe mitral regurgitation at rest3 (2.2%)0 (0.0%)2 (1.5%)
Wigle score6.2 (2.2)4.8 (2.6)5.3 (1.9)
Left ventricular outflow diameter (mm)17.2 (2.3)17.4 (2.5)18.8 (3.5)
E:A1.3 (0.5)1.4 (0.6)1.3 (0.4)
Resting left ventricular outflow tract gradient (mm Hg)57.7 (19.2)15.4 (8.7)10.1 (5.5)
  • All values expressed as mean (SD) or as n (%); NYHA, New York Heart Association; SAM, systolic anterior motion of the mitral valve; E:A, E-wave to A-wave ratio from mitral valve inflow Doppler.