Table 2 Predictors of major adverse outcomes
PredictorsOdds ratio (95% CI)Area under ROC curvep Value
Univariate analysis (controlling for time from baseline evaluation to most recent follow-up)
Age at TOF repair ⩾6 years7.78 (2.26 to 26.7)0.7480.001
Era of repair before 19704.05 (1.11 to 14.8)0.5910.035
RV end-diastolic volume Z ⩾74.98 (1.47 to 16.9)0.6880.01
RV end-systolic volume index >50 ml/m25.82 (1.22 to 27.7)0.7080.027
RV ejection fraction <45%5.31 (1.59 to 17.8)0.7500.007
LV ejection fraction <55%7.13 (2.11 to 24.0)0.7600.002
LV mass/volume ratio >1.54.56 (1.27 to 16.4)0.6880.02
QRS ⩾180 ms6.27 (1.86 to 21.1)0.6730.003
Diuretics at baseline evaluation7.68 (2.03 to 29.1)0.6460.003
Digoxin at baseline evaluation4.67 (1.30 to 16.8)0.6890.018
β-Blocker at baseline evaluation6.88 (1.12 to 42.3)0.6540.037
NYHA class II or III at baseline evaluation5.27 (1.55 to 17.9)0.7240.008
Multivariate analysis (controlling for time from baseline evaluation to most recent follow-up)
Model 1
    LV ejection fraction <55%8.05 (2.14 to 30.2)0.002
    RV end-diastolic volume Z ⩾74.55 (1.10 to 18.8)0.037
Area under ROC curve for the model: 0.850
Model 2
    RV ejection fraction <45%5.60 (1.47 to 21.2)0.011
    RV end-diastolic volume Z ⩾74.00 (1.10 to 14.6)0.036
Area under ROC curve for the model: 0.807
  • CI, confidence interval; LV, left ventricular; ROC, receiver operator characteristic; RV, right ventricular; TOF tetralogy of Fallot.