IL-10 quartile | Univariate | Model 1 | Model 2 | ||||||
Percentage (no. of events/total no.) | OR (95% CI) | p Value | Adj OR (95% CI) | p Value | Adj OR (95% CI) | p Value | |||
Death | 1 | 1.6% (13/805) | Reference | Reference | Reference | ||||
2 | 3.4% (27/797) | 1.9 (0.9 to 3.8) | 0.080 | 1.6 (0.8 to 3.2) | 0.234 | 1.4 (0.7 to 3.0) | 0.35 | ||
3 | 4.7% (37/789) | 2.7 (1.4 to 5.3) | 0.004 | 1.8 (0.9 to 3.6) | 0.105 | 1.5 (0.7 to 3.0) | 0.30 | ||
4 | 6.1% (48/788) | 3.4 (1.8 to 6.5) | <0.001 | 2.6 (1.3 to 5.1) | 0.007 | 1.7 (0.8 to 3.6) | 0.13 | ||
MI | 1 | 8.3% (67/805) | Reference | Reference | Reference | ||||
2 | 12.3% (98/797) | 1.5 (1.1 to 2.2) | 0.015 | 1.3 (0.9 to 1.9) | 0.134 | 1.3 (0.9 to 1.9) | 0.134 | ||
3 | 13.3% (105/789) | 1.7 (1.2 to 2.4) | 0.002 | 1.3 (0.9 to 1.9) | 0.107 | 1.4 (1.0 to 1.9) | 0.066 | ||
4 | 11.7% (92/788) | 1.5 (1.0 to 2.1) | 0.025 | 1.1 (0.8 to 1.6) | 0.476 | 1.3 (0.9 to 1.9) | 0.182 | ||
1 | 9.4% (76/805) | Reference | Reference | Reference | |||||
Composite of death/MI | 2 | 14.3% (114/797) | 1.5 (1.1 to 2.1) | 0.011 | 1.3 (0.9 to 1.8) | 0.130 | 1.3 (0.9 to 1.8) | 0.172 | |
3 | 16.0% (126/789) | 1.8 (1.3 to 2.5) | <0.001 | 1.4 (1.0 to 1.9) | 0.07 | 1.3 (1.0 to 1.9) | 0.095 | ||
4 | 15.6% (123/788) | 1.7 (1.2 to 2.3) | 0.002 | 1.3 (0.9 to 1.8) | 0.138 | 1.3 (0.9 to 1.8) | 0.190 |
Model 1 adjusted for age, sex, BMI, previous MI, hypertension, diabetes, ST-depression at entry, dalteparin/placebo, TnT>0.03 μg/l, cholesterol >5.5 mM, smoking, creatinine clearance, NT-pro-BNP, use of aspirin, ACE-inhibitor, β-blocker and statins. Model 2 included also CRP and IL-6>5 ng/l.