| Treatment | LVDP (mm Hg) | LVEDP (mm Hg) | ||||
| Baseline | 60 mins reperfusion | 120 mins reperfusion | Baseline | 60 mins reperfusion | 120 mins reperfusion | |
| C57BL/6 CON | 66.8 ± 1.4 | 10.3 ± 1.7 | 10.4 ± 1.6 | 4.2 ± 0.7 | 41.6 ± 2.7 | 29.3 ± 2.8 |
| C57BL/6 PostC | 67.0 ± 2.2 | 20.7 ± 4.0* | 21.5 ± 3.1* | 4.3 ± 0.5 | 29.5 ± 6.0* | 21.8 ± 5.2* |
| C57BL/6 SB15 | 68.4 ± 2.4 | 10.3 ± 3.3 | 11.5 ± 2.5 | 4.0 ± 0.5 | 47.4 ± 5.1 | 38.8 ± 4.6 |
| C57BL/6 SB120 | 67.1 ± 2.1 | 18.9 ± 1.7 | 10.0 ± 2.0 | 4.0 ± 0.4 | 47.4 ± 3.7 | 34.5 ± 5.4 |
| GSK-3ab KI CON | 66.3 ± 2.7 | 32.3 ± 3.6† | 28.3 ± 2.7† | 5.7 ± 0.5 | 34.6 ± 4.4† | 29.9 ± 3.6† |
| GSK-3ab KI PostC | 67.8 ± 3.8 | 44.4 ± 3.5† | 38.1 ± 2.9† | 5.2 ± 0.7 | 22.4 ± 4.2 | 18.9 ± 3.5 |
| GSK-3ab WT CON | 69.7 ± 3.6 | 13.7 ± 4.3 | 14.4 ± 10.7 | 6.6 ± 0.4 | 57.6 ± 6.1 | 49.6 ± 6.0 |
| GSK-3ab WT PostC | 65.4 ± 1.3 | 30.3 ± 3.4* | 28.4 ± 2.5* | 6.1 ± 0.7 | 31.4 ± 5.2* | 24.6 ± 4.1* |
CON, uninterrupted reperfusion; KI, knock-in; LVDP, left ventricular developed pressure; LVEDP, left ventricular end-diastolic pressure; PostC, 10 × 5 seconds reperfusion/5 seconds ischaemia; SB15, SB216763 for 15 minutes; SB120, SB216763 for 120 minutes; WT, wild-type.