Baseline characteristics
| Triglyceride quintile, mmol/l | ||||||
|---|---|---|---|---|---|---|
| Q1 (≤1.11) | Q2 (1.12–1.46) | Q3 (1.47–1.83) | Q4 (1.84–2.45) | Q5 (≥2.46) | ||
| N=369 | N=359 | N=369 | N=370 | N=369 | p Value* | |
| Age, years | 60±9 | 61±9 | 59±8 | 58±9 | 58±8 | <0.001 |
| Men, n (%) | 297 (81) | 296 (82) | 309 (84) | 324 (88) | 336 (91) | <0.001 |
| BMI, kg/m2 | 23±3 | 23±3 | 24±3 | 24±3 | 24±2 | <0.001 |
| Diabetes mellitus, n (%) | 149 (40) | 136 (38) | 132 (36) | 137 (37) | 149 (40) | 0.913 |
| Hypertension n (%) | 243 (66) | 238 (66) | 245 (66) | 257 (70) | 255 (69) | 0.211 |
| Total cholesterol, mmol/l | 5.12±1.22 | 5.53±1.11 | 5.82±1.19 | 5.92±1.34 | 6.23±1.22 | <0.001 |
| HDL cholesterol, mmol/l | 1.24±0.36 | 1.16±0.34 | 1.11±0.31 | 1.03±0.28 | 0.98±0.28 | <0.001 |
| Non-HDL cholesterol, mmol/l | 3.88±1.16 | 4.37±1.09 | 4.71±1.13 | 4.89±1.27 | 5.25±1.20 | <0.001 |
| Current smoker, n (%) | 260 (71) | 243 (68) | 272 (74) | 280 (76) | 304 (82) | <0.001 |
| Family history of CAD, n (%) | 126 (34) | 119 (33) | 102 (28) | 103 (28) | 125 (34) | 0.446 |
| Prior MI, n (%) | 147 (40) | 175 (49) | 170 (46) | 185 (50) | 204 (55) | <0.001 |
| Prior stroke, n (%) | 15 (4) | 24 (7) | 11 (3) | 14 (4) | 18 (5) | 0.720 |
| Atrial fibrillation, n (%) | 49 (13) | 47 (13) | 43 (12) | 38 (10) | 54 (15) | 0.985 |
| On dialysis (%) | 6 (1.6) | 1 (0.2) | 6 (1.6) | 7 (1.9) | 7 (1.9) | 0.283 |
| No of diseased vessels | 2.17±0.84 | 2.27±0.83 | 2.24±0.85 | 2.32±0.78 | 2.28±0.82 | 0.128 |
| LMT lesion, n (%) | 34 (9) | 21 (6) | 41 (11) | 29 (8) | 24 (7) | 0.437 |
| Arterial bypass to LAD, n (%) | 117 (32) | 112 (31) | 126 (34) | 124 (34) | 129 (35) | 0.791 |
| LVEF (%) | 65.3±12.7 | 64.0±12.9 | 65.3±11.9 | 63.9±13.5 | 63.4±13.4 | 0.136 |
| Revascularisation-isolated PCI, n (%) | 139 (38) | 117 (33) | 96 (26) | 98 (27) | 85 (23) | <0.001 |
| Medications, n (%) | ||||||
| Aspirin | 279 (76) | 264 (74) | 266 (72) | 253 (68) | 251 (68) | 0.006 |
| ACE inhibitors | 20 (5) | 16 (4) | 16 (4) | 24 (7) | 14 (4) | 0.729 |
| β-blockers | 88 (24) | 84 (23) | 113 (31) | 123 (33) | 111 (30) | 0.003 |
| Statins | 84 (23) | 60 (17) | 60 (16) | 67 (18) | 57 (16) | 0.035 |
| Fibrates | 3 (0.8) | 8 (2.2) | 10 (2.7) | 5 (1.4) | 7 (1.9) | 0.551 |
| Niacin | 37 (10) | 29 (8) | 28 (8) | 37 (10) | 23 (6) | 0.214 |
*p Value for trend for all comparisons across triglyceride quintiles.
BMI, body mass index; CAD, coronary artery disease; HDL, high-density lipoprotein; LAD, left anterior descending; LMT, left main trunk; LVEF, left ventricular ejection fraction; MI, myocardial infarction; PCI, percutaneous coronary intervention.