Table 3

HRs of heart failure according to different levels of serum GGT stratified by age, smoking status, alcohol consumption and BMI*

		Baseline GGT level
	Cases (n)	<25%	25 to <50%	50 to <75%	75 to <90%	≥90%	p for trend
Age at baseline (years)
25–60	655	1.00	1.36 (1.09–1.71)	1.30 (1.02–1.66)	1.41 (1.07–1.86)	1.90 (1.42–2.55)	0.001
60–74	426	1.00	0.93 (0.70–1.24)	1.10 (0.82–1.48)	1.03 (0.73–1.47)	1.43 (0.99–2.08)	0.173
Smoking status
Never or ever	737	1.00	1.02 (0.83–1.26)	1.14 (0.92–1.42)	1.21 (0.93–1.57)	1.67 (1.26–2.20)	0.004
Current	344	1.00	1.48 (1.06–2.08)	1.37 (0.97–1.95)	1.51 (1.02–2.25)	2.29 (1.51–3.46)	0.003
Alcohol consumption
Never drinker	614	1.00	1.13 (0.89–1.39)	1.13 (0.88–1.43)	1.50 (1.13–2.00)	1.99 (1.47–2.70)	<0.001
Alcohol drinker	467	1.00	1.20 (0.89–1.60)	1.32 (0.99–1.76)	1.15 (0.82–1.60)	1.80 (1.28–2.52)	0.010
Body mass index (kg/m²)
<25	239	1.00	1.21 (0.85–1.72)	1.60 (1.10–2.33)	1.99 (1.24–3.20)	3.28 (2.02–5.33)	<0.001
25–29.9	448	1.00	1.13 (0.88–1.47)	1.06 (0.80–1.41)	1.15 (0.83–1.60)	1.58 (1.10–2.26)	0.161
≥30	394	1.00	1.13 (0.80–1.61)	1.15 (0.81–1.63)	1.24 (0.85–1.82)	1.66 (1.12–2.45)	0.094

*Adjusting for age, study area, study year, smoking, education, alcohol consumption, physical activity, history of valvular heart disease, BMI, systolic blood pressure, total cholesterol at baseline and myocardial infarction, diabetes at baseline and during follow-up.
GGT, γ-glutamyltransferase.