Multivariable predictors of improvement in LV function with spironolactone therapy
| β | p Value | |
|---|---|---|
| ΔStrain (R2=0.32) | ||
| Baseline strain | −0.43 | 0.001 |
| ΔIB post | 0.26 | 0.02 |
| Baseline PICP | 0.24 | 0.04 |
| ΔSR (R2=0.40) | ||
| Baseline SR | −0.58 | 0.001 |
| ΔPIIINP | −0.21 | 0.04 |
| ΔEm (R2=0.35) | ||
| Baseline Em | −0.44 | 0.001 |
| Baseline PICP | 0.35 | 0.002 |
| BMI | 0.20 | 0.07 |
| ΔE/e′ (R2=0.19) | ||
| Baseline E/e′ | −0.35 | 0.005 |
| ΔPICP | 0.25 | 0.04 |
Δ, change with intervention; BMI, body mass index; Em, myocardial peak early diastolic velocity; IB post, calibrated integrated backscatter in the basal posterior wall; LV, left ventricular; PICP, procollagen type I C-terminal propeptide; SR, peak systolic strain rate.