Patients with risk factors for microcirculatory disease have a similar change in iFR and FFR produced by PCI
| Delta pre–post-PCI | ||||||
|---|---|---|---|---|---|---|
| Risk for microvascular disease | No of stenoses | FFR | iFR | Pd/Pa | iFR versus FFR | iFR versus Pd/Pa |
| Hypertension | ||||||
| No hypertension | 25 | 0.19±0.14 | 0.16±0.19 | 0.11±0.13 | 0.12 | <0.001 |
| Hypertension | 95 | 0.23±0.15 | 0.20±0.21 | 0.13±0.16 | 0.06 | <0.001 |
| p Value | 0.31 | 0.35 | 0.22 | |||
| Diabetes | ||||||
| No diabetes | 80 | 0.22±0.14 | 0.18±0.20 | 0.12±0.15 | 0.01 | <0.001 |
| Diabetes | 40 | 0.23±0.17 | 0.23±0.23 | 0.15±0.18 | 0.71 | <0.001 |
| p Value | 0.56 | 0.25 | 0.27 | |||
| Smoking status | ||||||
| Non-smoker | 72 | 0.16±0.19 | 0.18±0.19 | 0.12±0.15 | 0.11 | <0.001 |
| Smoker | 48 | 0.26±0.15 | 0.22±0.22 | 0.15±0.16 | 0.09 | <0.001 |
| p Value | 0.07 | 0.27 | 0.24 | |||
| Multiple risks | ||||||
| No risk factors | 9 | 0.14±0.13 | 0.13±0.17 | 0.09±0.12 | 0.85 | 0.04 |
| Diabetic, hypertensive, smoker | 13 | 0.22±0.14 | 0.22±−0.22 | 0.14±0.16 | 0.95 | 0.004 |
| 0.22 | 0.37 | 0.38 | ||||
Delta in indices was compared according to the presence of hypertension, diabetes and smoking status. ANOVA was performed with post hoc testing and Bonferroni correction.