HRs associated with long-term mortality from multiple Cox proportional hazards regression model fitted to the complete unmatched dataset
| HR | 95% CI | p Value | |
|---|---|---|---|
| Biological prosthesis | 1.05 | (0.93 to 1.19) | 0.434 |
| Age>75 years | 1.67 | (1.47 to 1.89) | <0.001 |
| BMI | |||
| Underweight (BMI<18.5) | 1.46 | (1.13 to 1.90) | 0.004 |
| Overweight (25≤BMI<30) | 0.83 | (0.72 to 0.94) | 0.005 |
| Obese (BMI≥30) | 1.00 | (0.84 to 1.18) | 0.956 |
| IV nitrates | 1.12 | (0.72 to 1.74) | 0.615 |
| Dyspnoea NYHA class IV | 1.31 | (1.11 to 1.55) | 0.002 |
| Neurological dysfunction | 1.10 | (0.81 to 1.49) | 0.557 |
| History of hypertension | 1.07 | (0.95 to 1.21) | 0.254 |
| Pulmonary hypertension | 1.07 | (0.91 to 1.27) | 0.396 |
| Previous MI | 1.09 | (0.91 to 1.30) | 0.344 |
| Creatinine>200 μmol/L | 1.88 | (1.39 to 2.54) | <0.001 |
| Chronic pulmonary disease | 1.45 | (1.25 to 1.68) | <0.001 |
| Extracardiac arteriopathy | 1.47 | (1.18 to 1.82) | 0.001 |
| Left ventricular function | |||
| Fair (LVEF 30–50%) | 1.20 | (1.05 to 1.36) | 0.006 |
| Poor (LVEF<30%) | 1.73 | (1.35 to 2.23) | <0.001 |
| Urgent | 1.31 | (1.13 to 1.52) | <0.001 |
| Critical preoperative state | 1.05 | (0.76 to 1.45) | 0.759 |
| TV repair | 1.37 | (1.13 to 1.65) | 0.001 |
| CABG | 1.18 | (1.03 to 1.36) | 0.015 |
Angina CCS class and diabetes were used as stratification variables for the baseline hazard funtion.
BMI, Body Mass Index; CABG, coronary artery bypass graft; IV, intravenous; LVEF, left ventricular ejection fraction NYHA, New York Heart Association; TV, tricuspid valve.