Patient baseline characteristics
| Preoperative variables | CsA (n=40) | Control (n=38) | p Value |
|---|---|---|---|
| Age (years) | 65.8 (10.7) | 67.1 (8.7) | 0.20 |
| Gender | 0.54 | ||
| Female | 13 (32.5) | 9 (24) | |
| Male | 27 (67.5) | 29 (76) | |
| Diabetes | 0.89 | ||
| None | 30 (75) | 28 (74) | |
| Non-IDDM | 9 (22.5) | 8 (21) | |
| IDDM | 1 (2.5) | 2 (5) | |
| Previous stroke | 2 (5) | 2 (5) | 0.96 |
| Hypertension | 29 (72.5) | 29 (76) | 0.90 |
| Peripheral vascular disease | 0 (0) | 0 (0) | |
| Hypercholesterolaemia | 29 (72.5) | 29 (76) | 0.90 |
| Previous MI | 21 (52.5) | 21 (55) | 0.99 |
| Smoker | 0.26 | ||
| Never | 15 (37.5) | 20 (53) | |
| Ex | 17 (42.5) | 11 (29) | |
| Current | 8 (20) | 7 (18) | |
| Family history of IHD | 19 (47.5) | 13 (34) | 0.36 |
| BMI | 28.8 (4.3) | 28.2 (3.5) | 0.55 |
| LVEF | 0.10 | ||
| >55% | 20 (50) | 27 (71) | |
| 35%–55% | 17 (42.5) | 10 (26) | |
| <35% | 3 (7.5) | 1 (2) | |
| Drug history | |||
| Aspirin | 34 (85) | 34 (89) | 0.80 |
| β-Blocker | 25 (62.5) | 31 (82) | 0.11 |
| Cholesterol-lowering drug | 31 (77.5) | 32 (84) | 0.64 |
| ACE inhibitor/AT2RB | 27 (67.5) | 27 (71) | 0.92 |
| Insulin | 3 (7.5) | 3 (8) | 0.95 |
| Metformin | 4 (10) | 6 (16) | 0.67 |
| EuroSCORE | 4.8 (2.9) | 4.6 (2.7) | 0.86 |
Data are mean (SD) or number (%).
BMI, body mass index; CsA, cyclosporin A; MI, myocardial infarct; IDDM, insulin-dependant diabetes mellitus; IHD, ischaemic heart disease.