Long-term clinical outcome
| Overall n=442 | MT n=78 | SAVR n=107 | TAVI n=257 | p diff. between groups | |
|---|---|---|---|---|---|
| At 3 years | |||||
| All-cause death | 182 (41.2%) | 55 (70.5%) | 33 (30.8%) | 94 (36.6%) | <0.001 |
| Cardiovascular death | 132 (29.9%) | 52 (66.7%) | 18 (16.8%) | 62 (24.1%) | <0.001 |
| MI | 7 (1.6%) | 2 (2.6%) | 0 (0.0%) | 5 (2.0%) | 0.266 |
| Major stroke | 23 (5.2%) | 3 (3.9%) | 8 (7.5%) | 12 (4.7%) | 0.463 |
| Minor stroke/TIA | 5 (1.1%) | 0 (0.0%) | 3 (2.8%) | 2 (0.8%) | 0.167 |
| All-cause death or major stroke | 189 (42.8%) | 56 (71.8%) | 36 (33.6%) | 97 (37.7%) | <0.001 |
| All-cause death, major stroke or MI | 192 (43.3%) | 57 (73.1%) | 36 (33.6%) | 99 (38.5%) | <0.001 |
| At 5 years | |||||
| All-cause death | 213 (48.2%) | 63 (80.8%) | 39 (36.5%) | 111 (43.2%) | <0.001 |
| Cardiovascular death | 157 (35.5%) | 60 (76.9%) | 24 (22.4%) | 73 (28.4%) | <0.001 |
| MI | 10 (2.3%) | 2 (2.6%) | 0 (0.0%) | 8 (3.1%) | 0.169 |
| Major stroke | 25 (5.7%) | 3 (3.9%) | 9 (8.4%) | 13 (5.1%) | 0.379 |
| Minor stroke/TIA | 6 (1.4%) | 0 (0.0%) | 3 (2.8%) | 3 (1.2%) | 0.316 |
| All-cause death or major stroke | 221 (50.0%) | 64 (82.1%) | 42 (39.3%) | 115 (44.8%) | <0.001 |
| All-cause death, major stroke or MI | 227 (51.4%) | 65 (83.3%) | 42 (39.3%) | 120 (46.7%) | <0.001 |
Values given are n (%) and the differences between groups were evaluated using Pearson's χ2 and Fisher's exact tests.
MI, myocardial infarction; MT, medical treatment; SAVR, surgical aortic valve replacement; TAVI, transcatheter aortic valve implantation; TIA, transient ischaemic attack.