Variable | LVEF group | EES | SES | PES | Adjusted HR | |||
---|---|---|---|---|---|---|---|---|
EES vs SES | p Value | EES vs PES | p Value | |||||
Overall definite ST | Moderate–severely impaired | 3 (0.03) | 14 (0.10) | 11 (0.16) | 0.28 (0.08–0.98) | 0.04 | 0.15 (0.04–0.55) | 0.004 |
Mildly impaired | 1 (0.01) | 22 (0.10) | 8 (0.07) | 0.11 (0.02–0.78) | 0.03 | 0.13 (0.02–0.99) | 0.047 | |
Normal | 3 (0.01) | 35 (0.06) | 26 (0.08) | 0.20 (0.06–0.71) | 0.01 | 0.12 (0.03–0.44) | 0.001 | |
Early definite ST | Moderate–severely impaired | 1 (0.29) | 7 (1.68) | 6 (3.31) | 0.21 (0.03–1.71) | 0.14 | 0.11 (0.01–0.89) | 0.04 |
Mildly impaired | 1 (0.28) | 5 (0.88) | 4 (1.37) | 0.44 (0.05–3.75) | 0.45 | 0.30 (0.02–2.83) | 0.15 | |
Normal | 2 (0.27) | 11 (0.71) | 5 (0.63) | 0.42 (0.09–1.91) | 0.26 | 0.67 (0.09–2.34) | 0.35 | |
Late definite ST | Moderate–severely impaired | 2 (0.02) | 7 (0.05) | 5 (0.08) | 0.37 (0.08–1.69) | 0.20 | 0.21 (0.04–1.07) | 0.06 |
Mildly impaired | 0 | 17 (0.08) | 4 (0.03) | N.A. | N.A. | N.A. | N.A. | |
Normal | 1 (0.00) | 24 (0.04) | 21 (0.06) | 0.05 (0.01–0.36) | 0.03 | 0.02 (0.00–0.18) | <0.0001 | |
Overall definite/probable ST | Moderate–severely impaired | 31 (0.31) | 53 (0.37) | 29 (0.44) | 0.70 (0.45–1.09) | 0.12 | 0.52 (0.31–0.88) | 0.02 |
Mildly impaired | 15 (0.15) | 38 (0.18) | 22 (0.18) | 0.67 (0.36–1.25) | 0.21 | 0.65 (0.33–1.30) | 0.22 | |
Normal | 19 (0.09) | 77 (0.13) | 47 (0.14) | 0.73 (0.44–1.20) | 0.21 | 0.47 (0.27–0.81) | 0.01 | |
Early definite/probable ST | Moderate–severely impaired | 26 (7.49) | 38 (9.14) | 18 (9.94) | 0.77 (0.47–1.28) | 0.32 | 0.73 (0.40–1.33) | 0.30 |
Mildly impaired | 11 (3.14) | 16 (2.81) | 11 (3.79) | 1.00 (0.45–2.21) | 0.99 | 0.71 (0.29–1.72) | 0.44 | |
Normal | 12 (1.65) | 23 (1.49) | 15 (1.90) | 1.18 (0.58–2.38) | 0.65 | 0.89 (0.41–1.90) | 0.75 | |
Late definite/probable ST | Moderate–severely impaired | 5 (0.05) | 15 (0.11) | 11 (0.17) | 0.48 (0.17–1.33) | 0.16 | 0.22 (0.07–0.71) | 0.01 |
Mildly impaired | 4 (0.04) | 22 (0.11) | 11 (0.09) | 0.41 (0.13–1.23) | 0.11 | 0.58 (0.19–1.78) | 0.34 | |
Normal | 7 (0.03) | 54 (0.09) | 32 (0.10) | 0.45 (0.20-.0.98) | 0.045 | 0.26 (0.11–0.61) | 0.002 | |
Death | Moderate–severely impaired | 59 (0.59) | 92 (0.61) | 43 (0.61) | 0.81 (0.58–1.13) | 0.22 | 0.78 (0.52–1.18) | 0.24 |
Mildly impaired | 27 (0.26) | 50 (0.23) | 32 (0.26) | 1.01 (0.61–1.67) | 0.96 | 0.93 (0.53–1.62) | 0.80 | |
Normal | 28 (0.13) | 91 (0.15) | 58 (0.17) | 0.84 (0.55–1.28) | 0.42 | 0.71 (0.45–1.11) | 0.13 | |
Cardiac death | Moderate–severely impaired | 47 (0.47) | 68 (0.45) | 35 (0.49) | 0.85 (0.58–1.25) | 0.42 | 0.75 (0.48–1.18) | 0.21 |
Mildly impaired | 21 (0.20) | 35 (0.16) | 26 (0.21) | 1.12 (0.64–1.98) | 0.69 | 0.83 (0.45–4.53) | 0.55 | |
Normal | 16 (0.07) | 50 (0.08) | 38 (0.11) | 0.85 (0.49–1.49) | 0.57 | 0.62 (0.35–1.11) | 0.11 | |
MI | Moderate–severely impaired | 6 (0.06) | 27 (0.19) | 16 (0.24) | 0.29 (0.12–0.70) | 0.01 | 0.19 (0.07–0.54) | 0.002 |
Mildly impaired | 11 (0.11) | 25 (0.12) | 17 (0.14) | 0.65 (0.35–1.57) | 0.44 | 0.65 (0.29–1.43) | 0.28 | |
Normal | 19 (0.09) | 74 (0.12) | 45 (0.14) | 0.77 (0.47–1.29) | 0.32 | 0.50 (0.29–0.87) | 0.01 |
Clinical outcome numbers are expressed as counts (number of events/month/100 patients). Adjusted risk ratios were calculated with the inverse probability of treatment weights as analytical weighting in Cox proportional hazards models.
EES, everolimus-eluting stent; MI, myocardial infarction; PES, paclitaxel-eluting stent; SES, sirolimus-eluting stent; ST, stent thrombosis.