Epilepsy and risk for SCD
| SCD cases n=926 | Controls n=9832 | OR* (95% CI) | OR† (95% CI) | |
|---|---|---|---|---|
| No epilepsy | 912 (98.4) | 9783 (99.5) | 1.0 (reference) | 1.0 (reference) |
| Epilepsy‡ | 14 (1.5) | 49 (0.5) | 2.7 (1.4 to 5.3) | 2.8 (1.4 to 5.3) |
| Stable epilepsy§ | 6 (0.6) | 37 (0.4) | 1.7 (0.7 to 4.2) | 1.6 (0.7 to 4.1) |
| Symptomatic epilepsy¶ | 8 (0.9) | 12 (0.1) | 5.9 (2.1 to 16.1) | 5.8 (2.1 to 15.6) |
Data are expressed as number (%) unless otherwise indicated.
*ORs matched for age, gender, practice, and calendar time.
†ORs matched for age, gender, practice, and calendar time, adjusted for heart failure.
‡Patients with a diagnosis of epilepsy and use of AEMs.
§Patients with a diagnosis of epilepsy, use of AEMs, and no seizure in the 2 years before SCD date.
¶Patients with a diagnosis of epilepsy, use of AEMs, and seizure in the 2 years before SCD date.
AEM, antiepileptic medication; SCD, sudden cardiac death.