Predictors of all-cause mortality at 5 years
| Alive | Dead | Univariate HR (95% CI) | p Value | Multivariate HR (95% CI) | p Value | |
|---|---|---|---|---|---|---|
| Type of intervention | <0.001 | <0.001 | ||||
| Medical | 15 (6.5%) | 63 (29.6%) | Reference | Reference | ||
| SAVR | 68 (29.7%) | 39 (18.3%) | 0.29 (0.19–0.43) | 0.39 (0.24–0.61) | ||
| TAVI | 146 (63.8%) | 111 (52.1%) | 0.34 (0.25–0.46) | 0.37 (0.26–0.52) | ||
| Age ≥80 years | 151 (65.9%) | 161 (75.6%) | 1.38 (1.01–1.89) | 0.045 | 1.39 (0.98–1.97) | 0.067 |
| Female | 132 (57.6%) | 98 (46.0%) | 0.70 (0.53–0.92) | 0.010 | 0.72 (0.53–0.99) | 0.042 |
| BMI ≤20 kg/m2 | 18 (7.9%) | 28 (13.2%) | 1.42 (0.94–2.15) | 0.091 | 1.60 (1.04–2.47) | 0.032 |
| Hypertension | 176 (76.9%) | 162 (76.1%) | 0.97 (0.71–1.33) | 0.851 | – | |
| Diabetes | 45 (19.7%) | 56 (26.3%) | 1.26 (0.93–1.72) | 0.136 | 1.48 (1.03–2.12) | 0.033 |
| Hypercholesterolaemia | 123 (53.7%) | 110 (51.6%) | 0.90 (0.69–1.18) | 0.463 | – | |
| History of CHD | 132 (57.6%) | 138 (64.8%) | 1.23 (0.93–1.65) | 0.139 | 1.13 (0.82–1.58) | 0.453 |
| History of MI | 34 (14.9%) | 45 (21.1%) | 1.33 (0.95–1.85) | 0.095 | 0.81 (0.55–1.21) | 0.306 |
| History of CABG | 34 (14.9%) | 42 (19.7%) | 1.27 (0.90–1.78) | 0.170 | 0.87 (0.57–1.34) | 0.529 |
| History of stroke | 14 (6.1%) | 30 (14.1%) | 1.94 (1.32–2.85) | 0.001 | 1.52 (1.00–2.32) | 0.051 |
| History of PVD | 31 (13.5%) | 62 (29.1%) | 1.90 (1.41–2.56) | <0.001 | 2.01 (1.44–2.81) | <0.001 |
| History of atrial fibrillation | 35 (15.3%) | 70 (32.9%) | 1.95 (1.46–2.60) | <0.001 | 1.74 (1.28–2.37) | <0.001 |
| LVEF <40% | 34 (16.5%) | 56 (27.9%) | 1.71 (1.26–2.33) | 0.001 | 1.25 (0.89–1.76) | 0.202 |
| Peak PA pressure ≥60 mm Hg | 40 (17.5%) | 55 (25.8%) | 1.50 (1.10–2.04) | 0.010 | 1.43 (1.03–2.00) | 0.034 |
Values given are n (%) or HR (95% CI). Only variables with a p value <0.25 in the univariate analysis were included in the multivariate model.
BMI, body mass index; CABG, coronary artery bypass grafting; CHD, coronary heart disease; MI, myocardial infarction; PA, pulmonary artery; PVD, peripheral vascular disease; SAVR, surgical aortic valve replacement; TAVI, transcatheter aortic valve implantation.