Baseline characteristics of the ARIC participants with and without SCD
| No SCD (n=14 688) | SCD (n=253) | p Value | |
|---|---|---|---|
| Age (years)* | 54.1 (5.8) | 56.5 (5.7) | <0.0001 |
| Female (%) | 55.6 | 33.2 | <0.0001 |
| African American (%) | 25.4 | 41.5 | <0.0001 |
| High school degree (%) | 77.0 | 58.1 | <0.0001 |
| Current smoker (%) | 25.9 | 40.7 | <0.0001 |
| Prevalent CHD (%) | 4.3 | 31.2 | <0.0001 |
| Prevalent MI (%) | 3.5 | 30.4 | <0.0001 |
| Prevalent heart failure (%) | 4.5 | 10.3 | <0.0001 |
| LVH at baseline ECG (%) | 2.0 | 7.9 | <0.0001 |
| Atrial fibrillation (%) | 0.2 | 0.8 | 0.06 |
| Weight (lbs)* | 172.7 (36.9) | 181.0 (37.1) | 0.0004 |
| Height (cm)* | 168.5 (9.3) | 170.1 (8.4) | 0.0005 |
| BMI (kg/m2)* | 27.6 (5.3) | 28.4 (5.4) | 0.01 |
| Waist circumference (cm)* | 96.8 (13.9) | 101.0 (14.1) | <0.0001 |
| Hip circumference (cm)* | 104.5 (10.3) | 103.9 (10.9) | 0.38 |
| Waist: hip ratio* | 0.92 (0.08) | 0.97 (0.06) | <0.0001 |
| Total cholesterol (mg/dL)* | 214.2 (41.4) | 220.0 (40.8) | 0.03 |
| HDL cholesterol (mg/dL)* | 51.9 (17.0) | 44.9 (13.4) | <0.0001 |
| LDL cholesterol (mg/dL)* | 137.3 (39.3) | 146.5 (38.5) | 0.0002 |
| Triglycerides (mg/dL)* | 124.7 (64.5) | 143.4 (72.1) | <0.0001 |
| Prevalent diabetes mellitus (%) | 10.9 | 32.0 | <0.0001 |
| Prevalent hypertension (%) | 33.5 | 61.7 | <0.0001 |
| Antihypertensive medication (%) | 29.5 | 56.9 | <0.0001 |
| Heart rate on ECG (beats/min)* | 66.6 (10.2) | 68.6 (12.1) | 0.002 |
| Systolic blood pressure (mm Hg) | 120.9 (18.6) | 133.3 (23.6) | <0.0001 |
| β-blockers, (%) | 10.1 | 21.0 | <0.0001 |
| Antiarrhythmic medications (%) | 0.7 | 3.2 | <0.0001 |
*Mean (SD).
ARIC, Atherosclerosis Risk in Communities; BMI, body mass index; CHD, coronary heart disease; HDL, high density lipoprotein; LDL, low density lipoprotein; LVH, LV hypertrophy; MI, myocardial infarction; SCD, sudden cardiac death.