Table 1

Expected to observed ratio of the prediction models in EPIC-NL, EPIC-Potsdam and SMART

Risk scoreExpected to observed ratio (95% CI)
EPIC-NLEPIC-PotsdamSMART
CVD prediction models11.5%3.7%5.7%
 Mukamal et al (CHS)191.06 (0.81 to 1.40)1.12 (0.83 to 1.50)1.23 (0.87 to 1.73)
 Kengne et al (ADVANCE)211.17 (0.90 to 1.54)1.22 (0.91 to 1.65)1.44 (1.02 to 2.02)
 Davis et al (Fremantle)221.18 (0.90 to 1.55)1.20 (0.89 to 1.62)1.46 (1.04 to 2.05)
 Elley et al (DCS)201.07 (0.82 to 1.41)1.08 (0.80 to 1.45)1.15 (0.82 to 1.62)
 Cederholm et al (NDR)231.14 (0.87 to 1.49)1.24 (0.92 to 1.66)1.34 (0.96 to 1.89)
CHD prediction models7.1%2.1%2.7%
 Elley et al (DCS)201.10 (0.78 to 1.56)1.11 (0.75 to 1.66)1.24 (0.76 to 2.02)
 Yang et al (HKDR)251.10 (0.78 to 1.56)1.12 (0.75 to 1.67)1.22 (0.75 to 1.99)
 Donnan et al (DARTS)241.18 (0.84 to 1.67)1.20 (0.81 to 1.78)1.55 (0.95 to 2.54)
 Folsom et al (ARIC)261.18 (0.85 to 1.69)1.12 (0.76 to 1.67)1.16 (0.71 to 1.90)
 Stevens et al (UKPDS)81.19 (0.85 to 1.69)1.33 (0.90 to 1.98)1.39 (0.85 to 2.27)
  • Displayed are the observed 5-year risks and the expected to observed ratio for each recalibrated risk score.

  • ADVANCE, Action in Diabetes and Vascular disease: preterAx and diamicroN-MR Controlled Evaluation; ARIC, Atherosclerosis Risk in Communities; CHD, coronary heart disease; CHS, Cardiovascular Health Study; CVD, cardiovascular disease; DARTS, Diabetes Audit and Research in Tayside Scotland; DCS, Diabetes Cohort Study; HKDR, Hong Kong Diabetes Register; NDR, National Diabetes Registry; SMART, Secondary Manifestations of ARTerial disease; UKPDS, UK Prospective Diabetes Study.