Predictors of AF progression
| Risk factor | Adjusted OR (95% CI) | t Value | p Value |
|---|---|---|---|
| AF or atrial flutter on baseline ECG | 2.30 (1.95 to 2.73) | 9.66 | <0.0001 |
| Heart Rate ≤80, bpm (per 10 decrease) | 0.84 (0.70 to 0.89) | 5.60 | <0.0001 |
| Age, years (per 10 increase) | 1.16 (1.09 to 1.24) | 4.48 | <0.0001 |
| NYHA class III/IV vs no heart failure | 1.61 (1.26 to 2.06) | 3.78 | 0.0002 |
| Moderate left atrial enlargement vs no enlargement | 1.35 (1.14 to 1.59) | 3.52 | 0.0004 |
| NYHA class II vs no heart failure | 1.38 (1.15 to 1.65) | 3.51 | 0.0005 |
| African American vs white | 0.56 (0.40 to 0.78) | −3.49 | 0.0005 |
| Mild left atrial enlargement vs no enlargement | 1.24 (1.07 to 1.42) | 2.93 | 0.0034 |
| Severe left atrial enlargement vs no enlargement | 1.30 (1.07 to 1.59) | 2.61 | 0.0101 |
| Anaemia* | 0.80 (0.67 to 0.97) | −2.30 | 0.0215 |
| Prior valve replacement or repair | 1.25 (1.03 to 1.52) | 2.22 | 0.0267 |
| NYHA class I vs no heart failure | 1.23 (1.02 to 1.48) | 2.18 | 0.0291 |
| Weight, kg (per 10 increase) | 1.03 (1.00 to 1.06) | 2.15 | 0.0317 |
| Persistent AF vs paroxysmal AF | 0.95 (0.74 to 1.22) | −0.40 | 0.6926 |
| Hispanic vs white | 1.04 (0.49 to 2.21) | 0.10 | 0.9201 |
| Other race vs white | 0.99 (0.62 to 1.60) | −0.02 | 0.9815 |
OR and 95% CI are attained by combining results from the five imputed data sets.
*Significant interaction between risk factor and baseline AF type.
AF, atrial fibrillation; NYHA, New York Heart Association.