Table 3

Univariate and multivariate analysis for risk analysis of mortality and major adverse cerebrovascular and cardiovascular events (MACCEs)

	Mortality				MACCEs
	Univariate		Multivariate		Univariate		Multivariate
	HR (95% CI)	p Value	HR (95% CI)	p Value	HR (95% CI)	p Value	HR (95% CI)	p Value
Age	1.15 (1.09 to 1.21)	0.01	1.10 (1.03 to 1.17)	0.01	1.06 (1.03 to 1.08)	0.01	1.05 (1.01 to 1.08)	0.01
Female	0.81 (0.43 to 1.53)	0.52			0.95 (0.60 to 1.51)	0.81
Weight	0.98 (0.95 to 1.00)	0.09	0.99 (0.96 to 1.03)	0.84	0.99 (0.97 to 1.01)	0.28	0.98 (0.95 to 1.02)	0.35
DM	0.78 (0.44 to 1.40)	0.40			1.15 (0.75 to 1.77)	0.52
Dyslipidemia	0.42 (0.21 to 0.84)	0.01	0.44 (0.21 to 0.92)	0.03	1.18 (0.76 to 1.82)	0.46
Last creatinine	1.96 (1.51 to 2.42)	0.01	1.40 (0.82 to 2.37)	0.22	1.59 (1.26 to 2.01)	0.01	1.41 (0.91 to 2.17)	0.13
Creatinine-based eGFR	0.97 (0.96 to 0.98)	0.01	0.99 (0.97 to 1.02)	0.58	0.99 (0.98 to 0.99)	0.01	1.04 (0.99 to 1.09)	0.11
PAOD	0.27 (0.14 to 0.53)	0.01	2.25 (1.08 to 4.70)	0.03	0.42 (0.24 to 0.73)	0.02	0.53 (0.25 to 1.12)	0.10
EuroSCORE	1.08 (1.05 to 1.12)	0.01	1.0 (0.93 to 1.08)	0.92	1.06 (1.03 to 1.10)	0.01	1.01 (0.94 to 1.08)	0.84
CHF	1.82 (0.56 to 5.89)	0.32			1.64 (0.59 to 4.54)	0.34
Arrhythmia	1.69 (0.52 to 5.50)	0.38			2.51 (1.08 to 5.85)	0.03	0.37 (0.14 to 0.99)	0.37
NYHA (III≤)	0.50 (0.04 to 6.86)	0.60			0.64 (0.06 to 7.05)	0.71
LVEF	0.98 (0.96 to 1.0)	0.02	0.98 (0.96 to 1.00)	0.10	0.99 (0.98 to 1.00)	0.1
Distal anastomosis	1.10 (0.78 to 1.54)	0.60			1.14 (0.84 to 1.56)	0.4
Pre. CK-MB	0.99 (0.98 to 1.02)	0.90			1.00 (0.99 to 1.01)	0.71
Pre. cystatin C	1.01 (0.96 to 1.07)	0.65			1.01 (0.95 to 1.07)	0.78
Cystatin C-based eGFR	0.97 (0.956 to 0.980)	0.01	0.98 (0.96 to 1.01)	0.24	0.99 (0.98 to 0.99)	0.01	0.99 (0.97 to 1.00)	0.58
Group
Mid vs low	1.14 (0.38 to 3.48)	0.80	0.37 (0.11 to 1.24)	0.11	1.06 (0.44 to 2.55)	0.89	0.65 (0.24 to 1.75)	0.39
High vs low	7.10 (2.64 to 19.12)	0.01	0.35 (0.14 to 0.83)	0.02	4.20 (1.86 to 9.46)	0.01	0.47 (0.21 to 1.03)	0.04

*p<0.05.
CHF, congestive heart failure; CK, creatine kinase; DM, diabetes mellitus; EDD, end-diastolic dimension; eGFR, estimated glomerular filtration rate; ESD, end-systolic dimension; EuroSCORE, European System for Cardiac Operative Risk Evaluation; NYHA, New York Heart Association; PAOD, peripheral artery occlusive disease.